Transcriptional regulation of PEBP1 expression by androgen receptor in mouse testes
Sign Up to like & getrecommendations! Published in 2021 at "Systems Biology in Reproductive Medicine"
DOI: 10.1080/19396368.2021.2004471
Abstract: ABSTRACT Androgen and AR are essential for maintaining spermatogenesis and male fertility. Previous studies have shown that the phosphatidyl ethanolamine binding protein 1 (Pebp1) gene is down-regulated in the selective ablation of the AR in… read more here.
Keywords: mouse testes; androgen receptor; androgen; gene ... See more keywords
LIN28A binds to meiotic gene transcripts and modulates their translation in male germ cells
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cell Science"
DOI: 10.1242/jcs.242701
Abstract: ABSTRACT The RNA-binding protein LIN28A is required for maintaining tissue homeostasis, including in the reproductive system, but the underlying mechanisms on how LIN28A regulates germline progenitors remain unclear. Here, we dissected LIN28A-binding targets using high-throughput… read more here.
Keywords: mouse testes; lin28a binds; null mouse; translation ... See more keywords
CD34 is Expressed in Endothelial Cells in Embryonic Testes and is Additionally Expressed in Non-Endothelial Cells in Postnatal Mouse Testes
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DOI: 10.2108/zs220026
Abstract: CD34 is expressed in various cell types in various tissues/organs, and has been regarded as being expressed in progenitors in various differentiation pathways. On the other hand, morphological studies have reported the presence of a… read more here.
Keywords: endothelial cells; non endothelial; mouse testes; cd34 expressed ... See more keywords
Phosphoproteomics of ATR signaling in mouse testes
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.68648
Abstract: The phosphatidylinositol 3′ kinase (PI3K)‐related kinase ATR is crucial for mammalian meiosis. ATR promotes meiotic progression by coordinating key events in DNA repair, meiotic sex chromosome inactivation (MSCI), and checkpoint-dependent quality control during meiotic prophase… read more here.
Keywords: atr; mouse testes; signaling mouse; atr signaling ... See more keywords