Early echocardiographic predictors of outcomes in the mouse transverse aortic constriction heart failure model.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of pharmacological and toxicological methods"
DOI: 10.1016/j.vascn.2016.12.001
Abstract: INTRODUCTION Mouse transverse aortic constriction (TAC) is a widely-used model of pressure overload-induced heart failure. An intrinsic limitation of the model is variability in the response to pressure overload even when employing a standard severity… read more here.
Keywords: end study; heart; aortic constriction; mouse transverse ... See more keywords
Abstract Wed012: Assessing Mouse Transverse Aortic Constriction Studies in AHA Journals for Reproducibility and Translational Potential
Sign Up to like & getrecommendations! Published in 2025 at "Circulation Research"
DOI: 10.1161/res.137.suppl_1.wed012
Abstract: Background: Mouse transverse aortic constriction (TAC) is a common technique to study heart failure. The hemodynamic severity of TAC is a main factor affecting cardiac outcomes with higher pressure gradients causing more fibrosis and heart… read more here.
Keywords: tac; severity; translational potential; mouse transverse ... See more keywords