The MOV10 RNA helicase is a dosage-dependent host restriction factor for LINE1 retrotransposition in mice
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Genetics"
DOI: 10.1101/2022.12.13.520206
Abstract: Transposable elements constitute nearly half of the mammalian genome and play important roles in genome evolution. While a multitude of both transcriptional and post-transcriptional mechanisms exist to silence transposable elements, control of transposition in vivo… read more here.
Keywords: mov10 rna; line1 retrotransposition; retrotransposition; mov10 ... See more keywords
Melatonin Regulates lncRNA NEAT1/miR-138-5p/HIF-1α Axis through MOV10 to Affect Acid-Related Esophageal Epithelial Cell Pyroptosis.
Sign Up to like & getrecommendations! Published in 2023 at "Pharmacology"
DOI: 10.1159/000530090
Abstract: INTRODUCTION Acid-related inflammatory damage to the esophageal epithelium is a key component in the development of gastroesophageal reflux disease. Melatonin (MT) is considered as a potential therapeutic agent, but its molecular mechanism is unknown. METHODS… read more here.
Keywords: acid related; lncrna neat1; mov10; mir 138 ... See more keywords
Moloney leukemia virus 10 (MOV10) inhibits the degradation of APOBEC3G through interference with the Vif-mediated ubiquitin–proteasome pathway
Sign Up to like & getrecommendations! Published in 2017 at "Retrovirology"
DOI: 10.1186/s12977-017-0382-1
Abstract: BackgroundMOV10 protein has ATP-dependent 5′–3′ RNA helicase activity and belongs to the UPF1p superfamily. It can inhibit human immunodeficiency virus type 1 (HIV-1) replication at multiple stages and interact with apolipoprotein-B-mRNA-editing enzyme catalytic polypeptide-like 3G… read more here.
Keywords: degradation; hiv; vif mediated; mov10 ... See more keywords
Effects of Moloney Leukemia Virus 10 Protein on Hepatitis B Virus Infection and Viral Replication
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DOI: 10.3390/v11070651
Abstract: Moloney leukemia virus 10 (MOV10) is an RNA helicase that has been shown to affect the replication of several viruses. The effect of MOV10 on Hepatitis B virus (HBV) infection is not known and its… read more here.
Keywords: protein; infection; hbv; mov10 ... See more keywords