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L-DOPA-elicited abnormal involuntary movements in the rats damaged severely in substantia nigra by 6-hydroxydopamine.

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Published in 2020 at "Annals of palliative medicine"

DOI: 10.21037/apm.2020.03.32

Abstract: BACKGROUND Dyskinesia of rat models can occur in several conditions: acute levodopa (L-DOPA) administration provided that the drug dose is sufficiently high and/or that the nigrostriatal dopamine (DA) pathway is seriously damaged, and repeated L-DOPA… read more here.

Keywords: abnormal involuntary; involuntary movements; dopa; substantia nigra ... See more keywords