Large-scale two-photon calcium imaging in freely moving mice
Sign Up to like & getrecommendations! Published in 2022 at "Cell"
DOI: 10.1016/j.cell.2022.02.017
Abstract: We developed a miniaturized two-photon microscope (MINI2P) for fast, high-resolution, multiplane calcium imaging of over 1,000 neurons at a time in freely moving mice. With a microscope weight below 3 g and a highly flexible connection… read more here.
Keywords: two photon; freely moving; moving mice; large scale ... See more keywords
A wireless miniScope for deep brain imaging in freely moving mice
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroscience Methods"
DOI: 10.1016/j.jneumeth.2019.05.008
Abstract: BACKGROUND The increasing interest in the study of neuronal activities at the microcircuit level is motivating neuroscientists and engineers to push the limits in developing miniature in vivo imaging systems. This inter-disciplinary effort led to… read more here.
Keywords: moving mice; wireless miniscope; miniscope; freely moving ... See more keywords
Stereotypical patterns of epileptiform calcium signal in hippocampal CA1, CA3, dentate gyrus and entorhinal cortex in freely moving mice
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-41241-x
Abstract: Epilepsy is a multi-etiological brain dysfunction syndrome. Hippocampal neuronal damage induced by seizures may be one of the causes leading to cognitive impairment, but the underlying mechanism remains to be further elucidated. The kainic acid… read more here.
Keywords: calcium signal; moving mice; epileptiform calcium; ca3 ... See more keywords
Simultaneous multi-target ultrasound neuromodulation in freely-moving mice based on a single-element ultrasound transducer
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Neural Engineering"
DOI: 10.1088/1741-2552/acb104
Abstract: Objective. Ultrasound neuromodulation has become an emerging method for the therapy of neurodegenerative and psychiatric diseases. The phased array ultrasonic transducer enables multi-target ultrasound neuromodulation in small animals, but the relatively large size and mass… read more here.
Keywords: target ultrasound; ultrasound neuromodulation; neuromodulation; moving mice ... See more keywords
Optrode recording of an entorhinal-cortical circuit in freely moving mice.
Sign Up to like & getrecommendations! Published in 2023 at "Biomedical optics express"
DOI: 10.1364/boe.487191
Abstract: The deep layers of medial entorhinal cortex (MEC) are considered a crucial station for spatial cognition and memory. The deep sublayer Va of MEC (MECVa) serves as the output stage of the entorhinal-hippocampal system and… read more here.
Keywords: single neuron; freely moving; circuit; mecva neurons ... See more keywords
Simultaneous Measurement of Neuronal Activity in the Pontine Micturition Center and Cystometry in Freely Moving Mice
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2019.00663
Abstract: Understanding the complex neural mechanisms controlling urinary bladder activity is an extremely important topic in both neuroscience and urology. Simultaneously recording of the bladder activity and neural activity in related brain regions will largely advance… read more here.
Keywords: neuronal activity; moving mice; bladder; freely moving ... See more keywords
Reusable Multielectrode Array Technique for Electroencephalography in Awake Freely Moving Mice
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Integrative Neuroscience"
DOI: 10.3389/fnint.2018.00053
Abstract: Translational comparison of rodent models of neurological and neuropsychiatric diseases to human electroencephalography (EEG) biomarkers in these conditions will require multisite rodent EEG on the skull surface, rather than local area electrocorticography (ECoG) or multisite… read more here.
Keywords: skull surface; moving mice; awake freely; freely moving ... See more keywords
Chronically implanted Neuropixels probes enable high-yield recordings in freely moving mice
Sign Up to like & getrecommendations! Published in 2019 at "eLife"
DOI: 10.7554/elife.47188
Abstract: The advent of high-yield electrophysiology using Neuropixels probes is now enabling researchers to simultaneously record hundreds of neurons with remarkably high signal to noise. However, these probes have not been well-suited to use in freely… read more here.
Keywords: freely moving; high yield; chronically implanted; moving mice ... See more keywords