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Sevoflurane depresses neurons in the medial parabrachial nucleus by potentiating postsynaptic GABAA receptors and background potassium channels

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Published in 2020 at "Neuropharmacology"

DOI: 10.1016/j.neuropharm.2020.108249

Abstract: Despite persistent clinical use for over 170 years, the neuronal mechanisms by which general anesthetics produce hypnosis remain unclear. Previous studies suggest that anesthetics exert hypnotic effects by acting on endogenous arousal circuits. Recently, it… read more here.

Keywords: medial parabrachial; potassium; hypnosis; gabaa ... See more keywords