Translational Nanotherapeutics Reprograms Immune Microenvironment in Malignant Pleural Effusion of Lung Adenocarcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202100149
Abstract: Malignant pleural effusion (MPE) remains a treatment bottleneck in advanced lung cancer, due to its complicated microenvironments and "cold" immunity. Therefore, the search for therapeutic drugs to transform MPE to functionally "hot" one could advance… read more here.
Keywords: microenvironment; mpe; malignant pleural; pleural effusion ... See more keywords
IL‐26 promotes the pathogenesis of malignant pleural effusion by enhancing CD4+IL‐22+ T‐cell differentiation and inhibiting CD8+ T‐cell cytotoxicity
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.1ma0221-479rr
Abstract: IL‐26 is a newly discovered IL‐10 cytokine family member mainly secreted by Th17 cells. However, the relationship between IL‐26 and lung cancer remains unclear. The present study reported that IL‐26 is involved in the production… read more here.
Keywords: mpe; cd4 cells; cd4; pleural effusion ... See more keywords
Mineralizing Pulmonary Elastosis in a Cat.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of comparative pathology"
DOI: 10.1016/j.jcpa.2021.06.007
Abstract: Mineralizing pulmonary elastosis (MPE) is a rare and unique phenomenon that has been reported in humans, typically secondary to recurrent pulmonary haemorrhage. MPE has a complex histopathological appearance, often containing iron-calcium deposits that can be… read more here.
Keywords: mpe; pulmonary elastosis; mineralizing pulmonary; elastosis cat ... See more keywords
Mycobacteriaceae Mineralizes Micropolyethylene in Riverine Ecosystems.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.2c05346
Abstract: Microplastic (MP) contamination is a serious global environmental problem. Plastic contamination has attracted extensive attention during the past decades. While physiochemical weathering may influence the properties of MPs, biodegradation by microorganisms could ultimately mineralize plastics… read more here.
Keywords: mineralizes micropolyethylene; micropolyethylene riverine; riverine ecosystems; mycobacteriaceae mineralizes ... See more keywords
Intrapleural nano-immunotherapy promotes innate and adaptive immune responses to enhance anti-PD-L1 therapy for malignant pleural effusion
Sign Up to like & getrecommendations! Published in 2021 at "Nature Nanotechnology"
DOI: 10.1038/s41565-021-01032-w
Abstract: Malignant pleural effusion (MPE) is indicative of terminal malignancy with a uniformly fatal prognosis. Often, two distinct compartments of tumour microenvironment, the effusion and disseminated pleural tumours, co-exist in the pleural cavity, presenting a major… read more here.
Keywords: mpe; malignant pleural; effusion; pleural effusion ... See more keywords
Treatment of malignant pleural effusion in non-small cell lung cancer with VEGF-directed therapy
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Medicine"
DOI: 10.1080/07853890.2022.2071977
Abstract: Abstract Background Vascular endothelial growth factor (VEGF) is a critical regulator of malignant pleural effusion (MPE) in non-small-cell lung cancer (NSCLC). Bevacizumab (BEV) and apatinib (APA) are novel VEGF blockers that inhibit lung cancer cell… read more here.
Keywords: vegf; mpe; lung cancer; pleural effusion ... See more keywords
Expanding knowledge on non‐expandable lungs
Sign Up to like & getrecommendations! Published in 2019 at "Respirology"
DOI: 10.1111/resp.13718
Abstract: Malignant pleural effusion (MPE) affects an estimated 150 000 patients and accounts for 126 000+ hospital admissions a year in the USA alone. In many MPE patients, the lung is unable to expand to the… read more here.
Keywords: incidence; mpe; pleurodesis; nel ... See more keywords
First pass effect of mechanical thrombectomy for acute vertebrobasilar artery occlusion: data from the ANGEL-ACT registry
Sign Up to like & getrecommendations! Published in 2023 at "Journal of NeuroInterventional Surgery"
DOI: 10.1136/jnis-2023-020065
Abstract: Background To explore the incidence, predictors, and association of first pass effect (FPE) on clinical outcomes of mechanical thrombectomy (MT) for acute vertebrobasilar artery occlusion (VBAO) in the Asian population. Methods We selected patients from… read more here.
Keywords: effect; pass effect; icr; first pass ... See more keywords
S129 Indwelling pleural catheter versus talc pleurodesis in adults with malignant pleural effusion: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "Thorax"
DOI: 10.1136/thorax-2018-212555.135
Abstract: Background Malignant pleural effusion (MPE) is an increasingly common condition. It can cause significant distress to patients and negatively impact their quality of life. Indwelling pleural catheters (IPC) have been widely used in the management… read more here.
Keywords: ipc; review; mpe; meta analysis ... See more keywords
γδT Cells in Lung Cancer Malignant Pleural Effusion: Friend? Foe?
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Respiratory Cell and Molecular Biology"
DOI: 10.1165/rcmb.2019-0080ed
Abstract: In an era of rapid advances in immunotherapy for solid tumors, relatively little is known about the immune tumor microenvironment (iTME) of malignant pleural effusions (MPEs) and how to leverage the iTME for an overall… read more here.
Keywords: gdt cells; mpe; lung cancer; cancer ... See more keywords
CSF1/CSF1R signaling mediates malignant pleural effusion formation
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.155300
Abstract: Malignant pleural effusion (MPE) is an incurable common manifestation of many malignancies. Its formation is orchestrated by complex interactions among tumor cells, inflammatory cells, and the vasculature. Tumor-associated macrophages present the dominant inflammatory population of… read more here.
Keywords: csf1r; pleural effusion; malignant pleural; csf1 ... See more keywords