Tailoring the properties of mPEG-PLLA nanoparticles for better encapsulation and tuned release of the hydrophilic anticancer drug
Sign Up to like & getrecommendations! Published in 2017 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-017-0372-9
Abstract: Gemcitabine is used as a first-line drug for treating many solid tumours. However, it suffers from a major drawback of strong side effects and short plasma half-life because of degradation by enzyme when administered intravenously.… read more here.
Keywords: release hydrophilic; mpeg plla; tuned release; drug ... See more keywords
Synthesis of MPEG-b-PLLA Diblock Copolymers and Their Crystallization Performance with PDLA and PLLA Composite Films
Sign Up to like & getrecommendations! Published in 2024 at "Materials"
DOI: 10.3390/ma17092105
Abstract: Methoxy poly(ethylene glycol)-block-poly(L-lactide) (MPEG-b-PLLA) has a wide range of applications in pharmaceuticals and biology, and its structure and morphology have been thoroughly studied. In the experiment, we synthesized MPEG-b-PLLA with different block lengths using the… read more here.
Keywords: plla; composite films; crystallization performance; mpeg plla ... See more keywords