Inhibition of mPGES-2 ameliorates non-alcoholic steatohepatitis by activating NR1D1 via heme.
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DOI: 10.1002/hep.32671
Abstract: BACKGROUND & AIMS Non-alcoholic fatty liver disease (NAFLD), a complex metabolic syndrome, has limited therapeutic options. Microsomal prostaglandin E synthase-2 (mPGES-2) was originally discovered as a prostaglandin E2 (PGE2 ) synthase; however, it does not… read more here.
Keywords: inhibition mpges; non alcoholic; mpges ameliorates; role mpges ... See more keywords