Articles with "mpl" as a keyword



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Concomitant and noncanonical JAK2 and MPL mutations in JAK2V617F‐ and MPLW515 L‐positive myelofibrosis

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Published in 2019 at "Genes"

DOI: 10.1002/gcc.22781

Abstract: Sequential genotyping for phenotype‐driver mutations in JAK2 (exon 14), CALR (exon 9), and MPL (exon 10) is recommended in patients with myeloproliferative neoplasms. Yet, atypical JAK2‐ and MPL‐mutations were described in some triple‐negative patients. Whether… read more here.

Keywords: mpl mutations; jak2 mpl; noncanonical jak2; mpl ... See more keywords
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Liposarcoma in children and young adults: a clinicopathologic and molecular study of 23 cases in one of the largest institutions of China

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Published in 2021 at "Virchows Archiv"

DOI: 10.1007/s00428-021-03076-8

Abstract: The incidence of pediatric liposarcoma is rare and most published cases lack systematic genetic analyses. We present clinicopathologic and genetic features of 23 liposarcomas aged read more here.

Keywords: children young; liposarcoma; adults clinicopathologic; mpl ... See more keywords
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Neuroprotective effect of monophosphoryl lipid A, a detoxified lipid A derivative, in photothrombotic model of unilateral selective hippocampal ischemia in rat

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Published in 2018 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2018.02.045

Abstract: HighlightsPhotothrombotic model of unilateral selective hippocampal ischemia caused learning and memory deficit.Immunologic preconditioning with MPL and LPS resulted in rehabilitation of damaged learning and memory function.Following immunological preconditioning, TLR4 receptor reprogramming protects against cerebral ischemic… read more here.

Keywords: selective hippocampal; model unilateral; ischemia; mpl ... See more keywords
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Impact of a gas diffusion layer's structural and textural properties on oxygen mass transport resistance in the cathode and performance of proton exchange membrane fuel cells

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Published in 2021 at "Electrochimica Acta"

DOI: 10.1016/j.electacta.2021.137752

Abstract: Abstract In this work, we used our previously developed method for determination of oxygen mass transport coefficients (k) to evaluate the effects of the gas diffusion layer (GDL) structure and texture on oxygen mass transfer… read more here.

Keywords: mpl; oxygen mass; transport; performance ... See more keywords
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Structural design of gas diffusion layer for proton exchange membrane fuel cell at varying humidification

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Published in 2020 at "Journal of Power Sources"

DOI: 10.1016/j.jpowsour.2020.228355

Abstract: Abstract Different structural gas diffusion layers (GDLs) have been prepared to improve the performance of proton exchange membrane fuel cells (PEMFCs). Density of microporous layer (MPL), pore structure of MPL and thickness of macroporous substrate… read more here.

Keywords: humidification; proton exchange; exchange membrane; gas ... See more keywords
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Accuracy of estimates of milk production per lactation from limited test-day and recall data collected at smallholder dairy farms

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Published in 2020 at "Livestock Science"

DOI: 10.1016/j.livsci.2019.103911

Abstract: Abstract Milk production per lactation (MPL) is a key metric of dairy farms. Accurate estimation of MPL requires regular recording, which is laborious and costly. In smallholder systems in the tropics, therefore, generally very few… read more here.

Keywords: mpl estimates; per lactation; test; mpl ... See more keywords
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Seagrass beds reveal high abundance of microplastic in sediments: A case study in the Baltic Sea.

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Published in 2021 at "Marine pollution bulletin"

DOI: 10.1016/j.marpolbul.2021.112417

Abstract: Microplastic (MPL) contamination in the marine environment is extensively studied yet little is known about the extent of MPL abundance in seagrass beds. The aim of this study was to evaluate MPL accumulation in coastal… read more here.

Keywords: mpl; abundance; seagrass beds; baltic sea ... See more keywords
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A phase 2 study of the bivalent VLP norovirus vaccine candidate in older adults; impact of MPL adjuvant or a second dose.

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Published in 2020 at "Vaccine"

DOI: 10.1016/j.vaccine.2020.06.011

Abstract: INTRODUCTION Acute norovirus gastroenteritis causes significant morbidity and in uncommon cases fatality in older adults. We investigated the safety and immunogenicity of bivalent virus-like particle (VLP) vaccine candidate formulations with and without monophosphoryl lipid A… read more here.

Keywords: age; vaccine candidate; mpl; vaccine ... See more keywords
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Mice with Calr mutations homologous to human CALR mutations only exhibit mild thrombocytosis

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Published in 2019 at "Blood Cancer Journal"

DOI: 10.1038/s41408-019-0202-z

Abstract: Calreticulin (CALR) exon 9 frameshift mutations, commonly detected in essential thrombocythemia (ET) and primary myelofibrosis patients, activate signal transducer and activator of transcription (STAT) proteins in the presence of Myeloproliferative Leukemia Virus (MPL) and induce… read more here.

Keywords: mpl; human calr; mild thrombocytosis; mice ... See more keywords
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Clinical and molecular characteristics of acute myeloid leukemia with MPL mutation

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Published in 2022 at "Hematology"

DOI: 10.1080/16078454.2022.2066244

Abstract: ABSTRACT Objectives The current study aimed to explore the incidence of MPL mutations and the clinical and molecular characteristics of AML with MPL mutation. Methods In total, 1509 patients with newly diagnosed AML were retrospectively… read more here.

Keywords: mpl mutations; mpl; molecular characteristics; clinical molecular ... See more keywords
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Spatial Accuracy Evaluation for Mobile Phone Location Data With Consideration of Geographical Context

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Published in 2020 at "IEEE Access"

DOI: 10.1109/access.2020.3043317

Abstract: In recent years, mobile phone location (MPL) data have been widely used to determine the spatial trajectories of users. Although this massive amount of MPL data can provide insight into human movement, definite conclusions cannot… read more here.

Keywords: mpl; mpl data; phone; model ... See more keywords