Polyphenol‐Functionalized Cubosomes as Thrombolytic Drug Carriers
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201151
Abstract: The safe administration of thrombolytic agents is a challenge for the treatment of acute thrombosis. Lipid‐based nanoparticle drug delivery technologies present opportunities to overcome the existing clinical limitations and deliver thrombolytic therapy with enhanced therapeutic… read more here.
Keywords: thrombolytic drug; pep mpn; lipid cubosomes; mpn coated ... See more keywords
Approach to MPN Symptom Assessment
Sign Up to like & getrecommendations! Published in 2017 at "Current Hematologic Malignancy Reports"
DOI: 10.1007/s11899-017-0399-5
Abstract: Purpose of ReviewMyeloproliferative neoplasms (MPNs) are recognized for their debilitating symptom burdens. The purpose of this review is to understand the complexity of the MPN symptom burden and identify how validated MPN Patient Reported Outcome… read more here.
Keywords: mpn symptom; mpn; symptom burden; disease burden ... See more keywords
Anemia with thrombocytosis in an elderly male: a case of myelodysplastic syndrome-myeloproliferative neoplasm with ringed sideroblasts and thrombocytosis
Sign Up to like & getrecommendations! Published in 2018 at "Hematology, Transfusion and Cell Therapy"
DOI: 10.1016/j.htct.2018.02.005
Abstract: yelodysplastic syndrome (MDS)-myeloproliferative neolasm (MPN) with ringed sideroblasts and thrombocytosis MDS/MPN-RS-T) is a rare entity categorized under the yelodysplastic-myeloproliferative group (MDS/MPN) in the ecent 2016 World Health Organization (WHO) update on he classification of myeloid… read more here.
Keywords: anemia; thrombocytosis; mpn; ringed sideroblasts ... See more keywords
Most probable number - loop mediated isothermal amplification (MPN-LAMP) for quantifying waterborne pathogens in
Sign Up to like & getrecommendations! Published in 2017 at "Journal of microbiological methods"
DOI: 10.1016/j.mimet.2016.11.010
Abstract: We are reporting a most probable number approach integrated to loop mediated isothermal technique (MPN-LAMP) focusing on Gram-negative Escherichia coli and Gram-positive Enterococcus faecalis bacterial cells without nucleic acids extraction. LAMP assays for uidA from… read more here.
Keywords: bacterial cells; lamp; probable number; mpn ... See more keywords
Shaken or stirred?: Comparison of methods for dispersion of Mycoplasma pneumoniae aggregates for persistence in vivo.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of microbiological methods"
DOI: 10.1016/j.mimet.2016.11.011
Abstract: BACKGROUND Mycoplasma pneumoniae (Mpn), one of the smallest self-replicating prokaryotes, is known to readily adhere to host cells and to form aggregates in suspension. Having only one cell membrane and no cell wall, mycoplasmas present… read more here.
Keywords: mpn; sonication; dispersion; mycoplasma pneumoniae ... See more keywords
Zinc-Epigallocatechin-3-gallate Network-Coated Nanocomposites against the Pathogenesis of Amyloid-Beta.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c20334
Abstract: The aggregation of amyloid beta (Aβ) is a hallmark of Alzheimer's disease (AD), a major cause of dementia and an unmet challenge in modern medicine. In this study, we constructed a biocompatible metal-phenolic network (MPN)… read more here.
Keywords: aggregation; network; amyloid beta; epigallocatechin gallate ... See more keywords
Enzyme Sensing Using 2-Mercaptopyridine-Carbonitrile Reporters and Surface-Enhanced Raman Scattering
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DOI: 10.1021/acsomega.2c00139
Abstract: The high sensitivity and functional group selectivity of surface-enhanced Raman scattering (SERS) make it an attractive method for enzyme sensing, but there is currently a severe lack of enzyme substrates that release SERS reporter molecules… read more here.
Keywords: surface enhanced; carbonitrile; mercaptopyridine carbonitrile; mpn ... See more keywords
Frequency of infections in 948 MPN patients: a prospective multicenter patient-reported pilot study
Sign Up to like & getrecommendations! Published in 2020 at "Leukemia"
DOI: 10.1038/s41375-020-0890-1
Abstract: Recently, several studies have reported on immunosuppression and infectious complications in patients with myeloproliferative neoplasms (MPN) receiving Janus kinase (JAK) inhibitor therapy (reviewed in [1]). These datasets included analyses of large multicenter trials comparing JAK… read more here.
Keywords: multicenter; pilot study; mpn; mpn patients ... See more keywords
Early detection of myeloproliferative neoplasms in a Danish general population study
Sign Up to like & getrecommendations! Published in 2021 at "Leukemia"
DOI: 10.1038/s41375-021-01159-8
Abstract: The chronic Philadelphia chromosome-negative myeloproliferative neoplasms (MPN) are characterized by elevated blood cell counts and distinct histological bone marrow changes. We [1] and others [2] have raised concerns about a considerable underdiagnosis of MPN in… read more here.
Keywords: population; mpn; blood; bone marrow ... See more keywords
Efficacy of CDK9 inhibition in therapy of post-myeloproliferative neoplasm (MPN) secondary (s) AML cells
Sign Up to like & getrecommendations! Published in 2022 at "Blood Cancer Journal"
DOI: 10.1038/s41408-022-00618-4
Abstract: Dear Editor, Signaling downstream of the pathogenetic mutations in JAK2, MPL, or calreticulin, along with co-occurring mutations in chromatin modifiers or transcription factors, results in dysregulated transcriptome and proteome that is responsible for the transformation… read more here.
Keywords: mpn saml; bay 1143572; treatment; post ... See more keywords
Myelodysplastic/myeloproliferative neoplasms with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T): Mayo-Moffitt collaborative study of 158 patients
Sign Up to like & getrecommendations! Published in 2022 at "Blood Cancer Journal"
DOI: 10.1038/s41408-022-00622-8
Abstract: The current World Health Organization (WHO) classification of myeloid malignancies includes myelodysplastic/myeloproliferative neoplasms with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T) as a distinct entity. Previous literature on predictors of survival was based on the provisional category… read more here.
Keywords: thrombocytosis; mds mpn; myeloproliferative neoplasms; myelodysplastic myeloproliferative ... See more keywords