Articles with "mpo aav" as a keyword



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The association of neutrophil-to-lymphocyte ratio with all-cause mortality in Chinese patients with MPO-ANCA associated vasculitis

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Published in 2020 at "Clinical and Experimental Medicine"

DOI: 10.1007/s10238-020-00629-0

Abstract: Neutrophil-to-lymphocyte ratio (NLR) has been recently reported to be a promising inflammatory marker to assess systemic inflammation in many disorders. However, there are only a few studies looking at NLR in patients with myeloperoxidase (MPO)-anti-neutrophil… read more here.

Keywords: patients mpo; vasculitis; cause mortality; mpo aav ... See more keywords

P0397OUTCOMES OF PROTEINASE 3- AND MYELOPEROXIDASE ANTI-NEUTROPHIL CYTOPLASMIC ANTIBODY ASSOCIATED VASCULITIS IN DENMARK 2014-2017

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Published in 2020 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfaa142.p0397

Abstract: Anti-neutrophil cytoplasmic antibody associated vasculitis (AAV) defines an uncommon group of autoimmune diseases with antibodies directed against proteinase 3 (PR3) or myeloperoxidase (MPO). Incidence rates of PR3- and MPO-AAV differ geographically, and current evidence based… read more here.

Keywords: pr3 mpo; aav; egfr; mpo aav ... See more keywords

The HLA region in ANCA-associated vasculitis: characterisation of genetic associations in a Scandinavian patient population

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Published in 2024 at "RMD Open"

DOI: 10.1136/rmdopen-2023-004039

Abstract: Objective The antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are inflammatory disorders with ANCA autoantibodies recognising either proteinase 3 (PR3-AAV) or myeloperoxidase (MPO-AAV). PR3-AAV and MPO-AAV have been associated with distinct loci in the human leucocyte… read more here.

Keywords: mpo aav; hla region; hla; pr3 aav ... See more keywords

CX3CL1-induced CD16+ monocytes extravasation in myeloperoxidase-ANCA-associated vasculitis correlates with renal damage

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.929244

Abstract: Background Monocytes are involved in the pathogenesis of ANCA-associated vasculitis (AAV). Monocyte/macrophages are the dominant infiltrating cells in the glomeruli of patients with myeloperoxidase-AAV (MPO-AAV). However, how human monocyte subsets extravasate to the kidney in… read more here.

Keywords: cd16 monocytes; renal damage; aav patients; mpo aav ... See more keywords

Association of HLA-class II alleles with risk of relapse in myeloperoxidase-antineutrophil cytoplasmic antibody positive vasculitis in the Japanese population

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1119064

Abstract: Background Disease relapse remains a major problem in the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). In European populations, HLA-DPB1*04:01 is associated with both susceptibility and relapse risk in proteinase 3-ANCA positive AAV. In… read more here.

Keywords: hla; risk relapse; relapse; population ... See more keywords

The plasma proteome reveals distinct signaling pathways associated with PR3-ANCA positive and MPO-ANCA positive vasculitis

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Published in 2025 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2025.1600754

Abstract: Objective Despite recent advances, the pathophysiological mechanisms underlying anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) remain incompletely understood, and comparative proteomic analyses of AAV subtypes are lacking. This study aimed to identify key molecular signaling pathways… read more here.

Keywords: mpo aav; aav; anca positive; pr3 aav ... See more keywords