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Published in 2020 at "Clinical and Experimental Medicine"
DOI: 10.1007/s10238-020-00629-0
Abstract: Neutrophil-to-lymphocyte ratio (NLR) has been recently reported to be a promising inflammatory marker to assess systemic inflammation in many disorders. However, there are only a few studies looking at NLR in patients with myeloperoxidase (MPO)-anti-neutrophil…
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Keywords:
patients mpo;
vasculitis;
cause mortality;
mpo aav ... See more keywords
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Published in 2020 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfaa142.p0397
Abstract: Anti-neutrophil cytoplasmic antibody associated vasculitis (AAV) defines an uncommon group of autoimmune diseases with antibodies directed against proteinase 3 (PR3) or myeloperoxidase (MPO). Incidence rates of PR3- and MPO-AAV differ geographically, and current evidence based…
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Keywords:
pr3 mpo;
aav;
egfr;
mpo aav ... See more keywords
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Published in 2024 at "RMD Open"
DOI: 10.1136/rmdopen-2023-004039
Abstract: Objective The antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are inflammatory disorders with ANCA autoantibodies recognising either proteinase 3 (PR3-AAV) or myeloperoxidase (MPO-AAV). PR3-AAV and MPO-AAV have been associated with distinct loci in the human leucocyte…
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Keywords:
mpo aav;
hla region;
hla;
pr3 aav ... See more keywords
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.929244
Abstract: Background Monocytes are involved in the pathogenesis of ANCA-associated vasculitis (AAV). Monocyte/macrophages are the dominant infiltrating cells in the glomeruli of patients with myeloperoxidase-AAV (MPO-AAV). However, how human monocyte subsets extravasate to the kidney in…
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Keywords:
cd16 monocytes;
renal damage;
aav patients;
mpo aav ... See more keywords
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1119064
Abstract: Background Disease relapse remains a major problem in the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). In European populations, HLA-DPB1*04:01 is associated with both susceptibility and relapse risk in proteinase 3-ANCA positive AAV. In…
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Keywords:
hla;
risk relapse;
relapse;
population ... See more keywords
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Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1600754
Abstract: Objective Despite recent advances, the pathophysiological mechanisms underlying anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) remain incompletely understood, and comparative proteomic analyses of AAV subtypes are lacking. This study aimed to identify key molecular signaling pathways…
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Keywords:
mpo aav;
aav;
anca positive;
pr3 aav ... See more keywords