Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
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DOI: 10.1038/s41586-020-2223-y
Abstract: A new coronavirus, known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the aetiological agent responsible for the 2019–2020 viral pneumonia outbreak of coronavirus disease 2019 (COVID-19)1–4. Currently, there are no targeted therapeutic agents… read more here.
Keywords: drug design; drug; mpro sars; structure mpro ... See more keywords
Antiviral activities of natural compounds and ionic liquids to inhibit the Mpro of SARS-CoV-2: a computational approach
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DOI: 10.1039/d1ra08604a
Abstract: The recalcitrant spread of the COVID-19 pandemic produced by the novel coronavirus SARS-CoV-2 is one of the most destructive occurrences in history. Despite the availability of several effective vaccinations and their widespread use, this line… read more here.
Keywords: mpro sars; activities natural; natural compounds; antiviral activities ... See more keywords
In silico discovery of novel inhibitors from Northern African natural products database against main protease (Mpro) of SARS-CoV-2
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DOI: 10.1080/07391102.2022.2040594
Abstract: Abstract The recent outbreak of COVID-19 (Coronavirus Disease 2019), caused by a novel SARS-CoV-2 virus, has led to public health emergencies worldwide where time is as important as equipment to save lives. Antimalarial drugs such… read more here.
Keywords: mpro sars; database; natural products; sars cov ... See more keywords
Zingiber officinale: Ayurvedic Uses of the Plant and In Silico Binding Studies of Selected Phytochemicals With Mpro of SARS-CoV-2
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DOI: 10.1177/1934578x211031766
Abstract: Among the large number of plants that are part of the Ayurvedic system of medicine in India and Bangladesh, Zingiber officinale Roscoe (Zingiberaceae), or ginger in English, holds a special place and is often referred… read more here.
Keywords: zingiber officinale; medicine; mpro sars; sars cov ... See more keywords