Tolerance induction and microglial engraftment after fetal therapy without conditioning in mice with mucopolysaccharidosis type VII
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DOI: 10.1126/scitranslmed.aay8980
Abstract: In utero therapy with recombinant enzyme or hematopoietic stem cells in MPS7 mice induces tolerance to missing enzyme and corrects brain microglia. When treating at birth is too late Mucopolysaccharidosis type VII (MPS7) is a… read more here.
Keywords: mucopolysaccharidosis type; mps7; type vii; mice ... See more keywords