Low sensitivity of the MPT64 identification test to detect lineage 5 of the Mycobacterium tuberculosis complex
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DOI: 10.1099/jmm.0.000846
Abstract: Purpose. Differentiation of the Mycobacterium tuberculosis complex (MTBc) from non‐tuberculous mycobacteria (NTM) is important for tuberculosis diagnosis and is a prerequisite for reliable phenotypic drug‐resistance testing. We evaluated the performance of the rapid MPT64 antigen… read more here.
Keywords: mpt64; sensitivity; mpt64 test; tuberculosis ... See more keywords
Improving diagnosis of tuberculous lymphadenitis by combination of cytomorphology and MPT64 immunostaining on cell blocks from the fine needle aspirates
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DOI: 10.1371/journal.pone.0276064
Abstract: Background Extra pulmonary tuberculosis (EPTB) constitutes 18% of all tuberculosis (TB) cases and tuberculous lymphadenitis (TBL) constitutes 20–40% of EPTB. Diagnosis of TBL is challenging because of the paucibacillary nature of the disease. Objective To… read more here.
Keywords: mpt64; cell blocks; tuberculous lymphadenitis; fine needle ... See more keywords
mpt64 mutations in Mycobacterium tuberculosis with negative MPT64 antigen assay results from a tertiary hospital in Southeastern China
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DOI: 10.3389/fmed.2025.1531853
Abstract: Background MPT64 protein is an effective marker for detecting Mycobacterium tuberculosis (MTB) in liquid culture and clinical tissue samples. However, some MTB clinical isolates test negative for this antigen because of varied mutation types across… read more here.
Keywords: negative mpt64; mpt64 antigen; antigen assay; mpt64 ... See more keywords