The Gender-Biased Effects of Intranasal MPTP Administration on Anhedonic- and Depressive-Like Behaviors in C57BL/6 Mice: the Role of Neurotrophic Factors
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DOI: 10.1007/s12640-018-9912-4
Abstract: Depression is a highly prevalent and debilitating non-motor symptom observed during the early stages of Parkinson’s disease (PD). Although PD prevalence is higher in men, the depressive symptoms in PD are more common in women.… read more here.
Keywords: administration; anhedonic depressive; like behaviors; depressive like ... See more keywords
A non-human primate model for stable chronic Parkinson’s disease induced by MPTP administration based on individual behavioral quantification
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DOI: 10.1016/j.jneumeth.2018.10.037
Abstract: BACKGROUND The guidelines for applying individual adjustments to macaques according to the severity of behavioral symptoms during 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment were provided to reproduce stable chronic Parkinsonism in a recent study (Potts et al., 2014).… read more here.
Keywords: human primate; administration; administration based; non human ... See more keywords