Articles with "mpxv" as a keyword



Genomic annotation and molecular evolution of monkeypox virus outbreak in 2022

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Published in 2022 at "Journal of Medical Virology"

DOI: 10.1002/jmv.28036

Abstract: Monkeypox virus (MPXV) has generally circulated in West and Central Africa since its emergence. Recently, sporadic MPXV infections in several nonendemic countries have attracted widespread attention. Here, we conducted a systematic analysis of the recent… read more here.

Keywords: mpxv 2022; genomic annotation; outbreak; mpxv ... See more keywords

Monkeypox viral detection in semen specimens of confirmed cases: A systematic review and meta‐analysis

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Published in 2022 at "Journal of Medical Virology"

DOI: 10.1002/jmv.28250

Abstract: The current literature shows increasing concerns about potential seminal transmission of monkeypox virus (MPXV). Accordingly, we aimed to understand better the potential presence of MPXV in the seminal fluids and others specimens obtained from MPX… read more here.

Keywords: semen specimens; meta analysis; confirmed cases; mpxv ... See more keywords

Evolution and marker mutations in different clades of monkeypox virus

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Published in 2023 at "Journal of Medical Virology"

DOI: 10.1002/jmv.28596

Abstract: Monkeypox (MPX) is a viral zoonotic infection caused by the monkeypox virus (MPXV) (1,2). It can spread not only from animals to humans but also from humans to humans and from the environment to humans… read more here.

Keywords: mutations different; different clades; marker mutations; mpxv ... See more keywords

Comparative Analysis of 2022 Outbreak MPXV and Previous Clade II MPXV

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Published in 2024 at "Journal of Medical Virology"

DOI: 10.1002/jmv.70023

Abstract: The 2022–2024 outbreak of MPOX is an important worldwide public health issue that has triggered significant concerns in the scientific community. MPOX is caused by monkeypox virus (MPXV) belonging to the Poxviridae family. The study… read more here.

Keywords: 2022 outbreak; mpxv previous; mpxv; outbreak ... See more keywords

MPXV: Update on Morphological and Morphogenesis Aspects Through Transmission and Scanning Electron Microscopies and 3D Reconstruction

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Published in 2025 at "Journal of Medical Virology"

DOI: 10.1002/jmv.70180

Abstract: An unprecedented global outbreak caused by the monkeypox virus (MPXV) prompted the World Health Organization to declare a public health emergency of international concern on July 23, 2022. Therapeutics and vaccines for MPXV are not… read more here.

Keywords: transmission scanning; microscopies reconstruction; morphogenesis; mpxv ... See more keywords

Insights on Mpox virus infection immunopathogenesis

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Published in 2023 at "Reviews in Medical Virology"

DOI: 10.1002/rmv.2426

Abstract: An immunocompromised status has been associated with more odds of being infected with Mpox virus (MPXV) and progressing to severe disease. This aligns with the importance of immune competence for MPXV control and clearance. We… read more here.

Keywords: virus infection; virology; insights mpox; infection immunopathogenesis ... See more keywords

Monkeypox Outbreak Reflecting Rising Search Trend and Concern in Nonendemic Countries: A Google Trend Analysis

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Published in 2022 at "Disaster Medicine and Public Health Preparedness"

DOI: 10.1017/dmp.2022.243

Abstract: Monkeypox virus (MPXV), a double-stranded DNA virus from the genusOrthopoxvirus, causes a re-emerging zoonotic disease named monkeypox (MPX).1 The first human MPX case was detected in the Democratic Republic of the Congo (DRC) in 1970.2… read more here.

Keywords: nonendemic countries; analysis; mpxv; search ... See more keywords

Monkeypox virus genomic accordion strategies

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Published in 2024 at "Nature Communications"

DOI: 10.1038/s41467-024-46949-7

Abstract: The 2023 monkeypox (mpox) epidemic was caused by a subclade IIb descendant of a monkeypox virus (MPXV) lineage traced back to Nigeria in 1971. Person-to-person transmission appears higher than for clade I or subclade IIa… read more here.

Keywords: genomic accordion; monkeypox virus; mpxv; subclade iib ... See more keywords

Genomic epidemiology of mpox virus during the 2022 outbreak in New York City

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Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-60486-x

Abstract: New York City (NYC) was a major hotspot during the 2022 multi-country Mpox virus (MPXV) outbreak in the U.S. To investigate the genomic characteristics of MPXV in NYC, we sequenced 1138 specimens from 758 individuals… read more here.

Keywords: epidemiology; new york; mpxv; york city ... See more keywords

Monkeypox virus spreads from cell-to-cell and leads to neuronal death in human neural organoids

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Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-61134-0

Abstract: In 2022-23, the world experienced the largest recorded monkeypox virus (MPXV) outbreak outside of endemic regions. Remarkably, cases of neurological manifestations were reported, some of which fatal. MPXV DNA and MPXV-specific antibodies were detected in… read more here.

Keywords: cell cell; neural organoids; human neural; monkeypox virus ... See more keywords

Next-gen novel nanocage-based multivalent vaccine candidate to tackle the rising menace of Mpox

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Published in 2025 at "NPJ Vaccines"

DOI: 10.1038/s41541-025-01174-1

Abstract: The recent emergence and global spread of the human Monkeypox virus (MPXV), including its transmission to non-endemic regions, have raised significant global health concerns. In this proof-of-concept study, we developed a recombinant protein-based MPXV vaccine… read more here.

Keywords: next gen; vaccine candidate; mpxv; vaccine ... See more keywords