Articles with "mrap2" as a keyword



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Elucidation of the dimeric interplay of dual MRAP2 proteins in the zebrafish

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Published in 2021 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.30321

Abstract: The melanocortin receptor accessory protein 2 (MRAP2) plays an essential role in the regulation of metabolic homeostasis and deletion of which results in severe obesity syndrome in mice and human. Mammalian MRAP2 is recognized as… read more here.

Keywords: dimeric interplay; dual mrap2; elucidation dimeric; interplay dual ... See more keywords
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Orange-spotted grouper melanocortin-4 receptor: modulation of signaling by MRAP2.

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Published in 2019 at "General and comparative endocrinology"

DOI: 10.1016/j.ygcen.2019.113234

Abstract: Melanocortin-4 receptor (MC4R) and melanocortin receptor accessory protein 2 (MRAP2) play important roles in the melanocortin system, and interaction of MC4R and MRAP2 is suggested to play pivotal role in energy balance of vertebrates. Orange-spotted… read more here.

Keywords: mc4r mrap2; mc4r; orange spotted; spotted grouper ... See more keywords
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MRAP2 regulates ghrelin receptor signaling and hunger sensing

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Published in 2017 at "Nature Communications"

DOI: 10.1038/s41467-017-00747-6

Abstract: Ghrelin is the only known circulating orexigenic hormone. It is primarily secreted by the stomach and acts at its receptor, the growth hormone secretagogue receptor 1a (GHSR1a), in the hypothalamus to signal hunger and promote… read more here.

Keywords: ghrelin receptor; regulates ghrelin; hunger; melanocortin receptor ... See more keywords
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MRAP2 Interaction with Melanocortin-4 Receptor in SnakeHead (Channa argus)

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Published in 2021 at "Biomolecules"

DOI: 10.3390/biom11030481

Abstract: The melanocortin-4 receptor (MC4R) plays an important role in the regulation of food intake and energy expenditure. Melanocortin-2 receptor accessory protein 2 (MRAP2) modulates trafficking, ligand binding, and signaling of MC4R. The Northern snakehead (Channa… read more here.

Keywords: melanocortin receptor; mrap2; snakehead mc4r; mc4r ... See more keywords