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Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30321
Abstract: The melanocortin receptor accessory protein 2 (MRAP2) plays an essential role in the regulation of metabolic homeostasis and deletion of which results in severe obesity syndrome in mice and human. Mammalian MRAP2 is recognized as…
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Keywords:
dimeric interplay;
dual mrap2;
elucidation dimeric;
interplay dual ... See more keywords
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Published in 2019 at "General and comparative endocrinology"
DOI: 10.1016/j.ygcen.2019.113234
Abstract: Melanocortin-4 receptor (MC4R) and melanocortin receptor accessory protein 2 (MRAP2) play important roles in the melanocortin system, and interaction of MC4R and MRAP2 is suggested to play pivotal role in energy balance of vertebrates. Orange-spotted…
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Keywords:
mc4r mrap2;
mc4r;
orange spotted;
spotted grouper ... See more keywords
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Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-00747-6
Abstract: Ghrelin is the only known circulating orexigenic hormone. It is primarily secreted by the stomach and acts at its receptor, the growth hormone secretagogue receptor 1a (GHSR1a), in the hypothalamus to signal hunger and promote…
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Keywords:
ghrelin receptor;
regulates ghrelin;
hunger;
melanocortin receptor ... See more keywords
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Published in 2021 at "Biomolecules"
DOI: 10.3390/biom11030481
Abstract: The melanocortin-4 receptor (MC4R) plays an important role in the regulation of food intake and energy expenditure. Melanocortin-2 receptor accessory protein 2 (MRAP2) modulates trafficking, ligand binding, and signaling of MC4R. The Northern snakehead (Channa…
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Keywords:
melanocortin receptor;
mrap2;
snakehead mc4r;
mc4r ... See more keywords