44 Body composition may be prognostic and predictive of clinical outcomes in metastatic renal cell carcinoma (mRCC) patients treated with immune checkpoint inhibitors (ICI)
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DOI: 10.1136/jitc-2020-sitc2020.0044
Abstract: Background Immune checkpoint inhibitors (ICI) have revolutionized the treatment of metastatic renal cell carcinoma (mRCC). Biomarkers for mRCC patients treated with ICI are limited, and body composition is underutilized in mRCC. We investigated the association… read more here.
Keywords: risk; patients treated; body composition; mrcc patients ... See more keywords
Abstract 2505: Comprehensive molecular and genomic characterization of pancreatic tropism in metastatic renal cell carcinoma
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DOI: 10.1158/1538-7445.sabcs18-2505
Abstract: Introduction & Objectives : Patients with metastatic renal cell carcinoma (mRCC) involving the pancreas have been shown to exhibit a relatively indolent course, yet the biologic explanation is unclear. We sought to characterize the genomic… read more here.
Keywords: renal cell; cell carcinoma; mrcc patients; pancreatic tropism ... See more keywords
Pattern of glycosylphosphatidylinositol-anchored 80 kD protein (GPI-80) expression in peripheral blood as a marker for myeloid-derived suppressor cells (MDSCs) in metastatic renal cell cancer (mRCC) patients.
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DOI: 10.1200/jco.2017.35.6_suppl.504
Abstract: 504Background: Metastatic renal cell cancer (mRCC) patients are afflicted with the immunosuppressed condition, and myeloid-derived suppressor cells (MDSCs) are considered to be associated with this condition. MDSCs are difficult to detect in peripheral blood as… read more here.
Keywords: peripheral blood; metastatic renal; mrcc patients; myeloid ... See more keywords
Expectations for overall survival in mRCC patients who were selected for upfront cytoreductive nephrectomy in the targeted therapy era.
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DOI: 10.1200/jco.2020.38.6_suppl.646
Abstract: 646Background: Surgical selection is critical to obtain the best outcomes for mRCC patients treated with cytoreductive nephrectomy (CN). Prior studies suggest that international metastatic disease ... read more here.
Keywords: expectations overall; survival mrcc; mrcc patients; cytoreductive nephrectomy ... See more keywords
Exploratory Pilot Study of Circulating Biomarkers in Metastatic Renal Cell Carcinoma
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DOI: 10.3390/cancers12092620
Abstract: Simple Summary The identification of biomarkers in response to therapeutic treatment is one of the main objectives of personalized oncology. Predictive biomarkers are particularly relevant for oncologists challenged by the busy scenario of possible therapeutic… read more here.
Keywords: renal cell; cell carcinoma; exploratory pilot; mrcc patients ... See more keywords