Articles with "mrck kinase" as a keyword



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Water mediated procedure for preparation of stereoselective oximes as inhibitors of MRCK kinase

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Published in 2020 at "Journal of Molecular Structure"

DOI: 10.1016/j.molstruc.2020.128699

Abstract: Abstract Stereoselective aldoximes, preferably Z form have been obtained from α-cyano substituted carbonyl conjugated alkenes. This reaction occurs through Michael addition type reaction followed by retro-Knoevenagel reaction without transition-metal catalysis via C–C bond cleavage. These… read more here.

Keywords: stereoselective oximes; preparation stereoselective; mediated procedure; water mediated ... See more keywords