Cross-species comparison of the metabolism and excretion of selexipag
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DOI: 10.1080/00498254.2018.1444814
Abstract: Abstract 1. The metabolism of the prostacyclin receptor agonist selexipag (NS-304; ACT-293987) and its active metabolite MRE-269 (ACT-333679) has been investigated in liver microsomes and hepatocytes of rats, dogs, and monkeys. MRE-269 formation is the… read more here.
Keywords: cross species; metabolism; selexipag; rats dogs ... See more keywords