Novel MRGPRX2 antagonists inhibit IgE‐independent activation of human umbilical cord blood‐derived mast cells
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DOI: 10.1002/jlb.2ab1018-405r
Abstract: Human MCs are primary effectors implicated in immune surveillance and defense by secreting histamine and various inflammatory mediators, a mechanism termed as degranulation. MCs can be activated by two pathways: IgE‐dependent classical pathway and the… read more here.
Keywords: novel mrgprx2; independent activation; ige independent; blood derived ... See more keywords