Investigating the contribution of hyaluronan to the breast tumour microenvironment using multiparametric MRI and MR elastography.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13437
Abstract: Hyaluronan (HA) is a key component of the dense extracellular matrix in breast cancer, and its accumulation is associated with poor prognosis and metastasis. Pegvorhyaluronidase alfa (PEGPH20) enzymatically degrades HA and can enhance drug delivery… read more here.
Keywords: contribution hyaluronan; elastography; breast tumour; investigating contribution ... See more keywords
Dosimetric feasibility of hippocampal avoidance whole brain radiotherapy with an MRI‐guided linear accelerator
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.13587
Abstract: Abstract Purpose/Objective(s) Whole brain radiotherapy with hippocampal avoidance (HA‐WBRT) is a technique utilized to treat metastatic brain disease while preserving memory and neurocognitive function. We hypothesized that the treatment planning and delivery of HA‐WBRT plans… read more here.
Keywords: brain; linear accelerator; radiotherapy; mri ... See more keywords
Technical note: Institutional solution of clinical cine MRI for tumor motion evaluation in radiotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.13650
Abstract: Abstract Purpose Since 4D‐MRI is inadequate to capture dynamic respiratory variations, real‐time cinematographic (cine) MRI is actively used in MR‐guided radiotherapy (MRgRT) for tumor motion evaluation, delineation, and tracking. However, most radiotherapy imaging platforms do… read more here.
Keywords: motion evaluation; tumor motion; cine; cine mri ... See more keywords
Development of a vendor neutral MRI distortion quality assurance workflow
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.13735
Abstract: Abstract With the utilization of magnetic resonance (MR) imaging in radiotherapy increasing, routine quality assurance (QA) of these systems is necessary. The assessment of geometric distortion in images used for radiotherapy treatment planning needs to… read more here.
Keywords: quality assurance; geometric distortion; scanner; distortion ... See more keywords
Muscle magnetic resonance imaging involvement patterns in nemaline myopathies.
Sign Up to like & getrecommendations! Published in 2023 at "Annals of clinical and translational neurology"
DOI: 10.1002/acn3.51816
Abstract: OBJECTIVE Characterise the diagnostic and prognostic value of muscle MRI patterns as biomarkers in a genetically heterogeneous nemaline myopathy (NM) patient cohort. METHODS Modified Mercuri scoring of lower limb MRI in genetically characterised NM patients… read more here.
Keywords: tpm3; neb acta1; involvement; adductor ... See more keywords
Self‐Confirming Magnetosomes for Tumor‐Targeted T1/T2 Dual‐Mode MRI and MRI‐Guided Photothermal Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200841
Abstract: Nanomaterials as T1/T2 dual‐mode magnetic resonance imaging (MRI) contrast agents have great potential in improving the accuracy of tumor diagnosis. Applications of such materials, however, are limited by the complicated chemical synthesis process and potential… read more here.
Keywords: guided photothermal; photothermal therapy; mri; mri guided ... See more keywords
Upregulating HIF‐1α to Boost the Survival of Neural Stem Cells via Functional Peptides‐Complexed MRI‐Visible Nanomedicine for Stroke Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201630
Abstract: Neural stem cells (NSCs) transplantation has been considered as a promising strategy for the treatment of ischemic stroke. However, the therapeutic prospect is limited by the poor control over the survival, migration, and maturation of… read more here.
Keywords: functional peptides; therapy; mri; stem ... See more keywords
Coordination‐Responsive Longitudinal Relaxation Tuning as a Versatile MRI Sensing Protocol for Malignancy Targets
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Science"
DOI: 10.1002/advs.201800021
Abstract: Abstract Biomarkers (e.g., acidity, H2O2, hypoxia, and specific molecules) as one primary component of tumor microenvironments are closely associated with occurrence, invasion, and metastasis of malignancy, thus can act as biological targets. However, their monitoring… read more here.
Keywords: coordination; longitudinal relaxation; relaxation tuning; malignancy ... See more keywords
Deep Learning for Brain MRI Confirms Patterned Pathological Progression in Alzheimer's Disease
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202204717
Abstract: Deep learning (DL) on brain magnetic resonance imaging (MRI) data has shown excellent performance in differentiating individuals with Alzheimer's disease (AD). However, the value of DL in detecting progressive structural MRI (sMRI) abnormalities linked to… read more here.
Keywords: alzheimer disease; progression; brain; mri ... See more keywords
Clinical and MRI Outcome Predictors in Pediatric Anti-NMDA Receptor Encephalitis.
Sign Up to like & getrecommendations! Published in 2020 at "Annals of neurology"
DOI: 10.1002/ana.25754
Abstract: OBJECTIVE To evaluate disease symptoms, clinical and MRI findings and to perform longitudinal volumetric MRI analyses in a European multi-center cohort of pediatric anti-NMDAR encephalitis (NMDARE) patients. METHODS We studied 38 children with NMDARE (median… read more here.
Keywords: outcome; clinical mri; pediatric anti; encephalitis ... See more keywords
Rapidly Progressing Honeycomb‐Like Germinoma in the Ventricular System
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Neurology"
DOI: 10.1002/ana.26075
Abstract: A 12-year-old boy was admitted to the hospital because of a 2-month history of dizziness and nausea. The neurological examination was unremarkable. Brain magnetic resonance imaging (MRI) revealed a multicystic lesion comprising multiple similar round… read more here.
Keywords: germinoma ventricular; ventricular system; honeycomb like; mri ... See more keywords