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   Articles with "mri contrast" as a keyword



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Metal-based environment-sensitive MRI contrast agents.

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recommendations! Published in 2021 at "Current opinion in chemical biology"

DOI: 10.1016/j.cbpa.2021.01.013

Abstract: Interactions of paramagnetic metal complexes with their biological environment can modulate their magnetic resonance imaging (MRI) contrast-enhancing properties in different ways, and this has been widely exploited to create responsive probes that can provide biochemical… read more here.

Keywords: metal based; environment; mri contrast; mri ... See more keywords
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Mn(III) porphyrins as potential MRI contrast agents for diagnosis and MRI-guided therapy

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recommendations! Published in 2021 at "Coordination Chemistry Reviews"

DOI: 10.1016/j.ccr.2021.214069

Abstract: Abstract Mn(III) porphyrins have great potential as Gd-free MRI contrast agents because both the cation and the ligand have interesting properties. The redox properties of the Mn(III)-ion can be exploited for the preparation of reactive… read more here.

Keywords: mri guided; iii porphyrins; mri; mri contrast ... See more keywords
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Magnetic hyperthermia efficiency and MRI contrast sensitivity of colloidal soft/hard ferrite nanoclusters.

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recommendations! Published in 2018 at "Journal of colloid and interface science"

DOI: 10.1016/j.jcis.2017.10.001

Abstract: The use of magnetic nanostructures as theranostic agents is a multiplex task as physiochemical and biochemical properties including excellent magneto-responsive properties, low toxicity, colloidal stability and facile surface engineering capability are all required. Nonetheless, much… read more here.

Keywords: efficiency mri; magnetic ncs; homo magnetic; mri contrast ... See more keywords
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Facile solvothermal synthesis and functionalization of polyethylene glycol-coated paramagnetic Gd2(CO3)3 particles and corresponding Gd2O3 nanoparticles for use as MRI contrast agents

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recommendations! Published in 2019 at "Journal of Science: Advanced Materials and Devices"

DOI: 10.1016/j.jsamd.2018.12.005

Abstract: Abstract Paramagnetic particles and nanoparticles have been widely used in bioimaging and biomedical applications. In this paper, functionalized gadolinium carbonate (Gd2(CO3)3) particles with polyethylene glycol (PEG) for use as an MRI contrast agent were produced.… read more here.

Keywords: gd2 co3; co3 particles; co3; mri contrast ... See more keywords
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Hyperbranched lipopolymer-folate-stabilized manganese ferrite nanoparticles for the water-soluble targeted MRI contrast agent

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recommendations! Published in 2019 at "Reactive and Functional Polymers"

DOI: 10.1016/j.reactfunctpolym.2019.104352

Abstract: Abstract A powerful T2-weighted magnetic resonance imaging (MRI) contrast agent with targetability has been fabricated by encapsulating manganese ferrite (MnFe2O4) nanoparticles (NPs) into biocompatible L-α-phosphatidylethanolamine-hyperbranched polyglycidol (PE–HBPG) bioconjugates covalently functionalized with folic acid (FA). The… read more here.

Keywords: contrast; mri contrast; water soluble; contrast agent ... See more keywords
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Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers.

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recommendations! Published in 2019 at "Chemical reviews"

DOI: 10.1021/acs.chemrev.8b00363

Abstract: Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are performed annually around the world. The contrast agents, which improve diagnostic accuracy, are almost exclusively small, hydrophilic gadolinium(III) based chelates. In recent years concerns… read more here.

Keywords: contrast agents; agents current; contrast; mri contrast ... See more keywords
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Metallostar Assemblies Based on Dithiocarbamates for Use as MRI Contrast Agents.

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recommendations! Published in 2020 at "Inorganic chemistry"

DOI: 10.1021/acs.inorgchem.0c01318

Abstract: Two different octadentate gadolinium chelates based on DO3A and DOTAGA chelates (hydration number q = 1) have been used to prepare a series of bi-, tri-, and tetrametallic d-f mixed-metal complexes. The piperazine-based dithiocarbamate linker… read more here.

Keywords: contrast agents; mri contrast; chemistry; gadolinium ... See more keywords
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Mn(II)-based MRI contrast agent candidate for vascular imaging.

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recommendations! Published in 2020 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.0c00197

Abstract: Toxicity concerns related to Gd(III)-based MRI agents prompted an intensive research towards their replacement by complexes of essential Mn(II) ion. Here, we report a macrocyclic chelate, [Mn(PC2A-BP)], which possesses high thermodynamic stability and kinetic inertness… read more here.

Keywords: based mri; mri contrast; contrast agent; mri ... See more keywords
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Manganese Complex of Ethylenediaminetetraacetic Acid (EDTA)-Benzothiazole Aniline (BTA) Conjugate as a Potential Liver-Targeting MRI Contrast Agent.

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recommendations! Published in 2017 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.6b01799

Abstract: A novel manganese(II) complex based on an ethylenediaminetetraacetic acid (EDTA) coordination cage bearing a benzothiazole aniline (BTA) moiety (Mn-EDTA-BTA) was designed and synthesized for use as a liver-specific MRI contrast agent with high chelation stability.… read more here.

Keywords: edta; mri contrast; liver; contrast agent ... See more keywords
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Osteoinductive superparamagnetic Fe nanocrystal/calcium phosphate heterostructured microspheres.

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recommendations! Published in 2017 at "Nanoscale"

DOI: 10.1039/c7nr06777a

Abstract: Functional magnetic and biocompatible particles are of great interest because of their potential use in various bioapplications such as hyperthermia for cancer treatment, magnetic resonance imaging (MRI) contrast agents and drug delivery. Herein, we introduce… read more here.

Keywords: fecap; calcium phosphate; mri contrast; heterostructured microspheres ... See more keywords
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Modular design of nanobody-drug conjugates for targeted-delivery of platinum anticancer drugs with an MRI contrast agent.

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recommendations! Published in 2019 at "Chemical communications"

DOI: 10.1039/c9cc01391a

Abstract: A multifunctional nanobody-drug conjugate (NDC) was constructed in this work for the targeted delivery of a platinum prodrug and an MRI contrast agent. The NDC can be specifically internalized into EGFR positive cancer cells, resulting… read more here.

Keywords: mri contrast; drug; contrast agent; nanobody drug ... See more keywords