RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types
Sign Up to like & getrecommendations! Published in 2019 at "Cell Reports"
DOI: 10.1016/j.celrep.2019.01.041
Abstract: Summary The molecular characterization of immune subsets is important for designing effective strategies to understand and treat diseases. We characterized 29 immune cell types within the peripheral blood mononuclear cell (PBMC) fraction of healthy donors… read more here.
Keywords: immune cell; absolute deconvolution; cell types; mrna abundance ... See more keywords
PSIV-5 Developmental and hormonal regulation of gene expression of fibrillin-1 (FBN1) and the asprosin receptor, olfactory receptor family 4 subfamily M member 1 (OR4M1), in bovine ovarian cells
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Animal Science"
DOI: 10.1093/jas/skaa278.510
Abstract: Asprosin is a novel fasting-induced protein associated with insulin resistance and polycystic ovaries in humans. It is encoded by FBN1 gene and produced when FBN1 is cleaved by the enzyme furin. In cattle, the role… read more here.
Keywords: receptor; fbn1; mrna abundance; fbn1 mrna ... See more keywords
Quantitating translational control: mRNA abundance-dependent and independent contributions and the mRNA sequences that specify them
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx898
Abstract: Abstract Translation rate per mRNA molecule correlates positively with mRNA abundance. As a result, protein levels do not scale linearly with mRNA levels, but instead scale with the abundance of mRNA raised to the power… read more here.
Keywords: mrna abundance; translation; translational control; mrna ... See more keywords
Abstract 2289: Precision-weighted RNA-seq analyses of molecular abundance (RoMA) for detecting differential gene expression
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-2289
Abstract: In this study, we propose a novel method, RoMA, to accurately detect differential expression and unlock the integration with numerous upstream and downstream analyses on mRNA abundance in RNA-seq studies. Various methods have been proposed,… read more here.
Keywords: abundance roma; abundance; rna seq; mrna abundance ... See more keywords
Caffeine Bitterness is Related to Daily Caffeine Intake and Bitter Receptor mRNA Abundance in Human Taste Tissue
Sign Up to like & getrecommendations! Published in 2017 at "Perception"
DOI: 10.1177/0301006616686098
Abstract: We investigated whether the abundance of bitter receptor mRNA expression from human taste papillae is related to an individual’s perceptual ratings of bitter intensity and habitual intake of bitter drinks. Ratings of the bitterness of… read more here.
Keywords: taste; caffeine; mrna abundance; bitterness ... See more keywords
Ruminal epithelial cell proliferation and short-chain fatty acid transporters in vitro are associated with abundance of period circadian regulator 2 (PER2).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of dairy science"
DOI: 10.3168/jds.2020-18767
Abstract: The major circadian clock gene PER2 is closely related to cell proliferation and lipid metabolism in various nonruminant cell types. Objectives of the study were to evaluate circadian clock-related mRNA abundance in cultured goat ruminal… read more here.
Keywords: per2; cell proliferation; abundance; mrna abundance ... See more keywords
Tumor necrosis factor-α reduces adiponectin production by decreasing transcriptional activity of peroxisome proliferator-activated receptor-γ in calf adipocytes.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of dairy science"
DOI: 10.3168/jds.2022-22919
Abstract: Adiponectin (encoded by ADIPOQ) is an adipokine that orchestrates energy homeostasis by modulating glucose and fatty acid metabolism in peripheral tissues. During the periparturient period, dairy cows often develop adipose tissue inflammation and decreased plasma… read more here.
Keywords: adiponectin; pparg; calf adipocytes; tnf ... See more keywords
Alterations in bacterial metabolites, cytokines, and mucosal integrity in the caecum of broilers caused by feed additives and host-related factors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.935870
Abstract: A total of 2,880 one-day-old male and female broiler chicks from two breeds, Ross308 and Cobb500 were randomly assigned to 72 pens. Broilers were offered three diets: a wheat-soybean diet without (CO), or with either… read more here.
Keywords: day; age; mrna abundance; integrity ... See more keywords
Decapping factor Dcp2 controls mRNA abundance and translation to adjust metabolism and filamentation to nutrient availability.
Sign Up to like & getrecommendations! Published in 2023 at "eLife"
DOI: 10.7554/elife.85545
Abstract: Degradation of most yeast mRNAs involves decapping by Dcp1/Dcp2. DEAD-box protein Dhh1 has been implicated as an activator of decapping, in coupling codon non-optimality to enhanced degradation, and as a translational repressor, but its functions… read more here.
Keywords: nutrient availability; dcp2; filamentation; abundance ... See more keywords