The 1H, 15N and 13C resonance assignments of the C-terminal domain of Serpine mRNA binding protein 1 (SERBP1).
Sign Up to like & getrecommendations! Published in 2021 at "Biomolecular NMR assignments"
DOI: 10.1007/s12104-021-10046-3
Abstract: SERBP1 is a multifunctional mRNA-binding protein that has been shown to play a regulatory role in a number of biological processes such as thrombosis, DNA damage repair, and the cellular response to nutrient deprivation. Additionally,… read more here.
Keywords: 15n 13c; mrna binding; binding protein; terminal domain ... See more keywords
Capturing the Mechanism Underlying TOP mRNA Binding to LARP1.
Sign Up to like & getrecommendations! Published in 2019 at "Structure"
DOI: 10.1016/j.str.2019.10.006
Abstract: The RNA-binding protein La-related protein 1 (LARP1) plays a central role in ribosome biosynthesis. Its C-terminal DM15 region binds the 7-methylguanosine (m7G) cap and 5' terminal oligopyrimidine (TOP) motif characteristic of transcripts encoding ribosomal proteins… read more here.
Keywords: underlying top; capturing mechanism; mrna binding; mechanism ... See more keywords
MDM2’s dual mRNA binding domains co-ordinate its oncogenic and tumour suppressor activities
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa431
Abstract: Abstract Cell growth requires a high level of protein synthesis and oncogenic pathways stimulate cell proliferation and ribosome biogenesis. Less is known about how cells respond to dysfunctional mRNA translation and how this feeds back… read more here.
Keywords: e2f1 mrna; mrna binding; tumour suppressor; translation ... See more keywords
The Roles of Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 in Cancer and Cancer Stem Cells
Sign Up to like & getrecommendations! Published in 2018 at "Stem Cells International"
DOI: 10.1155/2018/4217259
Abstract: RNA-binding proteins (RBPs) mediate the localization, stability, and translation of the target transcripts and fine-tune the physiological functions of the proteins encoded. The insulin-like growth factor (IGF) 2 mRNA-binding protein (IGF2BP, IMP) family comprises three… read more here.
Keywords: mrna binding; insulin like; growth factor; cancer ... See more keywords