mRNA Cancer Vaccines-Messages that Prevail.
Sign Up to like & getrecommendations! Published in 2017 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2017_509
Abstract: During the last decade, mRNA became increasingly recognized as a versatile tool for the development of new innovative therapeutics. Especially for vaccine development, mRNA is of outstanding interest and numerous clinical trials have been initiated.… read more here.
Keywords: mrna cancer; mrna vaccines; mrna; vaccines messages ... See more keywords
Abstract 854: Targeting Irg1 expressed on macrophages in lymph nodes promotes response to mRNA cancer vaccines
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-854
Abstract: mRNA cancer vaccines show great promise for tumor therapy, but their therapeutic efficacy is limited. Metabolites play critical roles in immunomodulation, however, their role in mRNA cancer vaccines remains unclear. Using metabolome analysis combined with… read more here.
Keywords: targeting irg1; cancer; mrna; lymph nodes ... See more keywords
Carbon dot-lipidoid nanocarriers for superiorly biocompatible nasal mRNA cancer vaccination
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-025-03844-7
Abstract: In this study, we synthesized an ionizable lipidoid, Cdoids, composed of carbon dots (Cdots) conjugated with oleic acid that exhibits superior biocompatibility compared to conventional ionizable lipids while retaining intrinsic fluorescence for real-time tracking and… read more here.
Keywords: delivery; carbon dot; mrna cancer; mrna ... See more keywords
mRNA Vaccines: The Dawn of a New Era of Cancer Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.887125
Abstract: mRNA therapy is a novel anticancer strategy based on in vitro transcription (IVT), which has potential for the treatment of malignant tumors. The outbreak of the COVID-19 pandemic in the early 21st century has promoted… read more here.
Keywords: mrna vaccines; immunotherapy; mrna cancer; cancer vaccines ... See more keywords