Simultaneous Binding of Multiple EF-Tu Copies to Translating Ribosomes in Live Escherichia coli
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DOI: 10.1128/mbio.02143-17
Abstract: ABSTRACT In bacteria, elongation factor Tu is a translational cofactor that forms ternary complexes with aminoacyl-tRNA (aa-tRNA) and GTP. Binding of a ternary complex to one of four flexible L7/L12 units on the ribosome tethers… read more here.
Keywords: mrna codon; amino; ternary complexes; elongation ... See more keywords
mRNA codon optimization with quantum computers
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DOI: 10.1371/journal.pone.0259101
Abstract: Reverse translation of polypeptide sequences to expressible mRNA constructs is a NP-hard combinatorial optimization problem. Each amino acid in the protein sequence can be represented by as many as six codons, and the process of… read more here.
Keywords: quantum computers; mrna codon; optimization quantum; optimization ... See more keywords