PABP Cooperates with the CCR4-NOT Complex to Promote mRNA Deadenylation and Block Precocious Decay.
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DOI: 10.1016/j.molcel.2018.05.009
Abstract: Multiple deadenylases are known in vertebrates, the PAN2-PAN3 (PAN2/3) and CCR4-NOT (CNOT) complexes, and PARN, yet their differential functions remain ambiguous. Moreover, the role of poly(A) binding protein (PABP) is obscure, limiting our understanding of the… read more here.
Keywords: decay; ccr4 complex; mrna deadenylation; pabp cooperates ... See more keywords