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   Articles with "mrna editing" as a keyword



Apolipoprotein-B mRNA-editing complex 3B could be a new potential therapeutic target in endometriosis

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recommendations! Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-76589-2

Abstract: This study investigated the correlation of Apolipoprotein-B mRNA-editing complex 3B (APOBEC3B) expression with hypoxia inducible factor 1α (HIF-1α), Kirsten rat sarcoma virus (KRAS) and phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) in endometriosis patients, and the… read more here.

Keywords: control sirna; cell; endometriosis; apolipoprotein mrna ... See more keywords

A-to-I mRNA editing recodes hundreds of genes in dozens of species and produces endogenous protein isoforms in bacteria

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recommendations! Published in 2025 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkaf656

Abstract: Abstract Adenosine-to-inosine (A-to-I) messenger RNA (mRNA) editing can affect the sequence and function of translated proteins and has been extensively investigated in eukaryotes. However, the prevalence of A-to-I mRNA editing in bacteria, its governing regulatory… read more here.

Keywords: recodes hundreds; protein; editing recodes; mrna editing ... See more keywords

Apolipoprotein B mRNA editing enzyme catalytic polypeptide‐like family genes activation and regulation during tumorigenesis

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recommendations! Published in 2018 at "Cancer Science"

DOI: 10.1111/cas.13658

Abstract: Cancer is currently viewed as a disease of evolving genomic instability and abnormal epigenomic modifications. Most solid cancers harbor oncogenic gene mutations driven by both extrinsic and intrinsic factors. Apolipoprotein B mRNA editing catalytic polypeptide‐like… read more here.

Keywords: catalytic polypeptide; like family; polypeptide like; mrna editing ... See more keywords
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Adaptive evolution at mRNA editing sites in soft-bodied cephalopods

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recommendations! Published in 2020 at "PeerJ"

DOI: 10.7717/peerj.10456

Abstract: Background The bulk of variability in mRNA sequence arises due to mutation—change in DNA sequence which is heritable if it occurs in the germline. However, variation in mRNA can also be achieved by post-transcriptional modification… read more here.

Keywords: soft bodied; evolution; selection; editing sites ... See more keywords