The G-Quadruplex-Specific RNA Helicase DHX36 Regulates p53 Pre-mRNA 3'-End Processing Following UV-Induced DNA Damage.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2016.11.033
Abstract: Pre-mRNA 3'-end processing, the process through which almost all eukaryotic mRNAs acquire a poly(A) tail is generally inhibited during the cellular DNA damage response leading to a profound impact on the level of protein expression… read more here.
Keywords: mrna end; dna damage; end processing; pre mrna ... See more keywords
Structural basis for mRNA 3′-end processing
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DOI: 10.1126/science.358.6366.1015-q
Abstract: Structural Biology The eukaryotic mRNA 3′-end processing machinery interacts with the transcription machinery and adds the polyadenylation tail on the mRNA substrate. Casanal et al. used cryo-electron microscopy, mass spectrometry, and biochemical reconstitutions to show… read more here.
Keywords: mrna end; structural basis; end processing; end ... See more keywords
UBE3D Regulates mRNA 3′-End Processing and Maintains Adipogenic Potential in 3T3-L1 Cells
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DOI: 10.1128/mcb.00174-22
Abstract: We have previously described the role of an essential Saccharomyces cerevisiae gene, important for cleavage and polyadenylation 1 (IPA1), in the regulation of gene expression through its interaction with Ysh1, the endonuclease subunit of the… read more here.
Keywords: mrna end; regulation; end; end processing ... See more keywords
Modulation of mRNA 3′-End Processing and Transcription Termination in Virus-Infected Cells
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DOI: 10.3389/fimmu.2022.828665
Abstract: Eukaryotic mRNA 3´-end processing is a multi-step process beginning with pre-mRNA transcript cleavage followed by poly(A) tail addition. Closely coupled to transcription termination, 3´-end processing is a critical step in the regulation of gene expression,… read more here.
Keywords: transcription termination; mrna end; end; end processing ... See more keywords