Exosomal TUBB3 mRNA expression of metastatic castration‐resistant prostate cancer patients: Association with patient outcome under abiraterone
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Medicine"
DOI: 10.1002/cam4.4168
Abstract: To use ddPCR to quantify plasma exosomal class III β‐tubulin (βIII‐tubulin, TUBB3, encoded by the TUBB3 gene) mRNA expression in metastatic castration‐resistant prostate cancer (mCRPC) patients, and study the association of this expression with abiraterone… read more here.
Keywords: expression metastatic; metastatic castration; expression; castration resistant ... See more keywords
Impact of adolescent stress on the expression of stress‐related receptors in the hippocampus of animals exposed to alcohol prenatally
Sign Up to like & getrecommendations! Published in 2018 at "Hippocampus"
DOI: 10.1002/hipo.22823
Abstract: Many functions of the hippocampus are affected by prenatal alcohol exposure (PAE). In particular, dysregulation of the stress response is especially important because individuals with PAE carry increased risks for exposure to stressful environments throughout… read more here.
Keywords: expression stress; stress related; related receptors; stress ... See more keywords
Integrating analysis of circular RNA and mRNA expression profiles in doxorubicin induced cardiotoxicity mice
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4257
Abstract: Doxorubicin (DOX)‐induced cardiotoxicity impedes its clinical application, but the mechanisms have not been thoroughly elucidated. Based on circRNA and mRNA expression profiles, we illustrated RNA expression signature changes during DOX‐induced cardiotoxicity; mechanism exploration and biomarkers… read more here.
Keywords: expression profiles; dox induced; induced cardiotoxicity; mrna expression ... See more keywords
Integrative analysis of transcriptome-wide association study data and mRNA expression profiles identified candidate genes and pathways associated with atrial fibrillation
Sign Up to like & getrecommendations! Published in 2019 at "Heart and Vessels"
DOI: 10.1007/s00380-019-01418-w
Abstract: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia characterized by extensive structural, contractile and electrophysiological remodeling. The genetic basis of AF remained elusive until now. Transcriptome-wide association study (TWAS) was conducted by FUSION… read more here.
Keywords: candidate; expression; candidate genes; association study ... See more keywords
Effect of long-term treatment with classical neuroleptics on NPQ/spexin, kisspeptin and POMC mRNA expression in the male rat amygdala
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-018-1868-2
Abstract: Neuroleptics modulate the expression level of some regulatory neuropeptides in the brain. However, if these therapeutics influence the peptidergic circuits in the amygdala remains unclear. This study specifies the impact profile of the classical antipsychotic… read more here.
Keywords: rat amygdala; spexin; kisspeptin pomc; expression ... See more keywords
The 3′-UTR (CA)n microsatellite on CD40LG gene as a possible genetic marker for rheumatoid arthritis in Mexican population: impact on CD40LG mRNA expression
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Rheumatology"
DOI: 10.1007/s10067-017-3853-9
Abstract: The objective of this study was to determine the association of the CD40LG 3′-UTR (CA)n microsatellite with rheumatoid arthritis (RA) and CD40LG mRNA levels in females from western Mexico. A case-control study with 219 RA… read more here.
Keywords: utr microsatellite; cd40lg mrna; rheumatoid arthritis; mrna expression ... See more keywords
PRL -1149T allele (rs1341239) is associated with decreased risk of rheumatoid arthritis in population from southern Mexico: analysis of mRNA expression and PRL serum levels
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Rheumatology"
DOI: 10.1007/s10067-019-04517-1
Abstract: IntroductionProlactin (PRL) is a sex hormone with immunomodulatory properties, and it is associated with the clinical activity of rheumatoid arthritis (RA). The -1149G>T polymorphism at the prolactin (PRL) gene has been associated with autoimmune diseases,… read more here.
Keywords: prl serum; southern mexico; serum levels; expression ... See more keywords
JAK2 and PTPRC mRNA expression in peripheral blood mononuclear cells from patients with systemic lupus erythematosus
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Rheumatology"
DOI: 10.1007/s10067-019-04778-w
Abstract: In this study, we aimed to explore the expression levels of JAK2 and PTPRC in peripheral blood mononuclear cells (PBMCs) from SLE patients and controls, detect the effects of SLE activity on genes mRNA expression,… read more here.
Keywords: ptprc mrna; jak2 ptprc; expression; expression levels ... See more keywords
Obesity-alleviating potential of asiatic acid and its effects on ACC1, UCP2, and CPT1 mRNA expression in high fat diet-induced obese Sprague–Dawley rats
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-017-3199-2
Abstract: The present study evaluated the effects of asiatic acid (AA), a pentacyclic triterpenoid from Centella asiatica on lipid metabolism parameters in a rat model of obesity induced using a high fat diet (HFD) for 42 days.… read more here.
Keywords: fat diet; cpt1 mrna; high fat; expression ... See more keywords
Effects of exposure to 5-MeO-DIPT during adolescence on brain neurotransmission and neurotoxicity in adult rats
Sign Up to like & getrecommendations! Published in 2018 at "Forensic Toxicology"
DOI: 10.1007/s11419-018-0433-x
Abstract: PurposeTryptamine hallucinogen 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a serotonin transporter inhibitor with high affinity for serotonin 5-HT1A and 5-HT2A/C receptors. We showed previously that 5-MeO-DIPT in a single dose increased neurotransmitter release in brain regions of rats… read more here.
Keywords: dipt; ht1a ht2a; meo dipt; adult rats ... See more keywords
Subchronic Arsenism Disorders mRNA Expression of Cytokines and Immunoglobulins in the Intestinal Tract of the Cock
Sign Up to like & getrecommendations! Published in 2017 at "Biological Trace Element Research"
DOI: 10.1007/s12011-017-1073-4
Abstract: Provision of feed containing arsenic may cause intestinal flora imbalance and consequently, the dysfunction of immunological protection of the cock. To understand the intricate tuning of immune responses in the intestinal tract elicited by subchronic… read more here.
Keywords: cock; subchronic arsenism; intestinal tract; mrna expression ... See more keywords