Long-term GABA administration improves FNDC5, TFAM, and UCP3 mRNA expressions in the skeletal muscle and serum irisin levels in chronic type 2 diabetic rats.
Sign Up to like & getrecommendations! Published in 2022 at "Naunyn-Schmiedeberg's archives of pharmacology"
DOI: 10.1007/s00210-022-02211-9
Abstract: In this study, we aimed to investigate whether the anti-diabetic effects of γ-aminobutyric acid (GABA) and insulin can be mediated through the regulation of gene expression related to irisin production and mitochondrial biogenesis in type… read more here.
Keywords: irisin levels; diabetic rats; insulin; mrna expressions ... See more keywords
Thymoquinone alleviates mitochondrial viability and apoptosis in diclofenac-induced acute kidney injury (AKI) via regulating Mfn2 and miR-34a mRNA expressions
Sign Up to like & getrecommendations! Published in 2020 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-020-11313-x
Abstract: The current study was prepared to assess the underlying mechanism of diclofenac (Diclo)-stimulated renal oxidative damage (50 mg/kg/day for two consecutive days I.P) and antioxidative, and antiapoptotic effects of Thymoquinone (20 mg/kg/day for 21 days… read more here.
Keywords: mir 34a; mrna expressions; mfn2 mir; 34a mrna ... See more keywords
CgIL17-5 regulates the mRNA expressions of immune effectors through inducing the phosphorylation of CgMAPKs and the nuclear translocation of CgRel and CgAP-1 in the Pacific oyster Crassostrea gigas.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2021.104263
Abstract: Interleukin-17 (IL-17) is a classic pro-inflammatory cytokine that plays an important role in the immune and inflammatory response. In the present study, the sequence feature of CgIL17-5 and its function as a pro-inflammatory factor in… read more here.
Keywords: cgil17; mrna expressions; cgrel cgap; nuclear translocation ... See more keywords
Mechanical model of steady-state and inflammatory conditions in patients with relapsing polychondritis
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DOI: 10.1097/md.0000000000028852
Abstract: Abstract Relapsing polychondritis (RP) is a multisystem inflammatory disorder, considered to associate with immune aberration. Increased T helper type-1 cell-related cytokines were reported in RP patients. mRNA expressions of a regulatory T cell cytokine interleukin… read more here.
Keywords: mechanical model; model steady; relapsing polychondritis; steady state ... See more keywords
Systematic Characterization of Prognostic Values of Peroxiredoxin Family in Gastric Cancer
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DOI: 10.1155/2020/3948183
Abstract: The peroxiredoxin (PRDX) gene family has been reported to participate in regulating occurrence and development of cancerous diseases, but its exact prognostic values in gastric cancer (GC) remain largely elusive. In the current research, we… read more here.
Keywords: gastric cancer; family; prognostic values; mrna expressions ... See more keywords
[Diammonium glycyrrhizinate promotes the regeneration and repair of central nervous system in rats with severe traumatic brain injury by Wnt/β-catenin signaling pathway].
Sign Up to like & getrecommendations! Published in 2019 at "Zhonghua wei zhong bing ji jiu yi xue"
DOI: 10.3760/cma.j.issn.2095-4352.2019.12.004
Abstract: OBJECTIVE To observe the effects of diammonium glycyrrhizinate (DG) on nerve regeneration repair in rats with severe traumatic brain injury (STBI) from the perspective of Wnt/β-catenin signaling pathway. METHODS Seventy-two Sprague-Dawle (SD) male rats were… read more here.
Keywords: treatment; normal group; group; model ... See more keywords
Combination of berberine and ciprofloxacin reduces multi-resistant Salmonella strain biofilm formation by depressing mRNA expressions of luxS, rpoE, and ompR
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Veterinary Science"
DOI: 10.4142/jvs.2018.19.6.808
Abstract: Bacterial biofilms have been demonstrated to be closely related to clinical infections and contribute to drug resistance. Berberine, which is the main component of Coptis chinensis, has been reported to have efficient antibacterial activity. This… read more here.
Keywords: combination; salmonella; biofilm formation; mrna expressions ... See more keywords