Nanoflare Couple: Multiplexed mRNA Imaging and Logic-Controlled Combinational Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c02689
Abstract: Theranostics, which combines both diagnostic and therapeutic capabilities in one dose, has always been an intractable challenge in personalized cancer treatment. Herein, a versatile nanotheranostic platform "nanoflare couple (NC)" has been developed for in situ… read more here.
Keywords: nanoflare couple; therapy; mrna imaging; logic controlled ... See more keywords
Quantitative mRNA imaging throughout the entire Drosophila brain
Sign Up to like & getrecommendations! Published in 2017 at "Nature Methods"
DOI: 10.1038/nmeth.4309
Abstract: We describe a fluorescence in situ hybridization method that permits detection of the localization and abundance of single mRNAs (smFISH) in cleared whole-mount adult Drosophila brains. The approach is rapid and multiplexable and does not… read more here.
Keywords: drosophila; mrna imaging; imaging throughout; quantitative mrna ... See more keywords
Fluorescent turn-on probes for wash-free mRNA imaging via covalent site-specific enzymatic labeling††Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc03150e Click here for additional data file.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Science"
DOI: 10.1039/c7sc03150e
Abstract: Investigating the many roles RNA plays in cellular regulation and function has increased demand for tools to explore RNA tracking and localization within cells. read more here.
Keywords: mrna imaging; probes wash; free mrna; turn probes ... See more keywords