Why mRNA-ionizable LNPs formulations are so short-lived: causes and way-out
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DOI: 10.1080/17425247.2023.2162876
Abstract: ABSTRACT Introduction Messenger ribonucleic acid (mRNA) and small interfering RNA (siRNA) are biological molecules that can be heated, frozen, lyophilized, precipitated, or re-suspended without degradation. Currently, ionizable lipid nanoparticles (LNPs) are a promising approach for… read more here.
Keywords: life; storage; ionizable lnps; mrna ionizable ... See more keywords