SA107 ELEVATED PERIPHERAL EXPRESSION OF NEUREGULIN-1 (NRG1) MRNA ISOFORMS IN PATIENTS WITH TREATMENT-RESISTANT SCHIZOPHRENIA
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.179
Abstract: Background Differential expression of Neuregulin-1 (NRG1) mRNA isoforms and proteins has been reported in schizophrenia, primarily in post-mortem brain tissue. In this study, we examined 12 NRG1 SNPs, eight NRG1 mRNA isoforms (type I, type… read more here.
Keywords: protein; clozapine; nrg1 mrna; expression ... See more keywords
PSI-B-14 Late-Breaking: Evaluation of mRNA isoforms expression profile using two approaches to measure meat tenderness from Longissimus thoracis muscle in beef cattle
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Animal Science"
DOI: 10.1093/jas/skz258.642
Abstract: The Warner-Bratzler shear force (WBSF) and myofibrillar fragmentation index (MFI) are complementary methodologies commonly used to measure beef tenderness. To identify mRNA isoforms differentially expressed became an important tool to provide new insights to better… read more here.
Keywords: beef; muscle; measure; mrna isoforms ... See more keywords
Upregulation of SPS100 gene expression by an antisense RNA via a switch of mRNA isoforms with different stabilities
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx737
Abstract: Abstract Pervasive transcription of genomes generates multiple classes of non-coding RNAs. One of these classes are stable long non-coding RNAs which overlap coding genes in antisense direction (asRNAs). The function of such asRNAs is not… read more here.
Keywords: antisense; gene expression; expression; mrna isoforms ... See more keywords
Noncanonical Alternative Polyadenylation Contributes to Gene Regulation in Response to Hypoxia[OPEN]
Sign Up to like & getrecommendations! Published in 2017 at "Plant Cell"
DOI: 10.1105/tpc.16.00746
Abstract: Stress affects the production and fate of alternative mRNA isoforms to coordinate and fine-tune the adaptation of plants to the environment. Stresses from various environmental challenges continually confront plants, and their responses are important for… read more here.
Keywords: response; mrna isoforms; hypoxia; alternative polyadenylation ... See more keywords
CRISPR-Mediated Knockout of Long 3′ UTR mRNA Isoforms in mESC-Derived Neurons
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.789434
Abstract: Alternative cleavage and polyadenylation (APA) is pervasive, occurring for more than 70% of human and mouse genes. Distal poly(A) site selection to generate longer 3′ UTR mRNA isoforms is prevalent in the nervous system, affecting… read more here.
Keywords: mrna isoforms; derived neurons; mesc derived; utr mrna ... See more keywords
Identification of Novel mRNA Isoforms Associated with Acute Heat Stress Response Using RNA Sequencing Data in Sprague Dawley Rats
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11121740
Abstract: Simple Summary Global warming and events of heat waves even in temperate climatic zones signify the importance of the genetic makeup of heat stress. Our earlier acute heat stress exposure study (from 30 min to… read more here.
Keywords: mrna isoforms; acute heat; heat stress; heat ... See more keywords
Identification of Candidate mRNA Isoforms for Prostate Cancer-Risk SNPs Utilizing Iso-eQTL and sQTL Methods
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232012406
Abstract: Single nucleotide polymorphisms (SNPs) impacting the alternative splicing (AS) process (sQTLs) or isoform expression (iso-eQTL) are implicated as important cancer regulatory elements. To find the sQTL and iso-eQTL, we retrieved prostate cancer (PrCa) tissue RNA-seq… read more here.
Keywords: prca; iso eqtl; mrna isoforms; iso ... See more keywords