Effect of pH-Responsive Ligands on mRNA Knockdown in EGFR-Targeting Ligand-Conjugated siRNAs.
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DOI: 10.1021/acschembio.4c00507
Abstract: Ligand-conjugated small interfering RNAs (siRNAs) have emerged as a powerful approach to developing nucleic acid-based medicines. To achieve efficient mRNA knockdown, it is important to select targeting receptors with high expression and ligands that exhibit… read more here.
Keywords: effect; ligand; ligand receptor; mrna knockdown ... See more keywords