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   Articles with "mrna methylation" as a keyword



m6A mRNA methylation-directed myeloid cell activation controls progression of NAFLD and obesity.

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recommendations! Published in 2021 at "Cell reports"

DOI: 10.1016/j.celrep.2021.109968

Abstract: N6-methyladenosine (m6A) RNA modification is a fundamental determinant of mRNA metabolism, but its role in innate immunity-driven non-alcoholic fatty liver disease (NAFLD) and obesity is not known. Here, we show that myeloid lineage-restricted deletion of… read more here.

Keywords: nafld obesity; m6a mrna; mrna methylation; obesity ... See more keywords
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Epitranscriptomics and Flowering: mRNA Methylation/Demethylation Regulates Flowering Time[OPEN]

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recommendations! Published in 2017 at "Plant Cell"

DOI: 10.1105/tpc.17.00929

Abstract: DNA modifications such as methylation serve as epigenetic markers that influence gene expression and function. The importance of similar modifications in RNA is gaining appreciation, leading to the emergence of epitranscriptomic analyses. RNA modifications appear… read more here.

Keywords: epitranscriptomics flowering; methylation; demethylation regulates; mrna methylation ... See more keywords
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m6A mRNA methylation in human brain is disrupted in Lewy body disorders

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recommendations! Published in 2023 at "Neuropathology and Applied Neurobiology"

DOI: 10.1111/nan.12885

Abstract: N6‐methyladenosine modification of RNA (m6A) regulates translational control, which may influence neuronal dysfunction underlying neurodegenerative diseases. read more here.

Keywords: disrupted lewy; methylation human; mrna methylation; human brain ... See more keywords
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m6A mRNA Methylation Controls Functional Maturation in Neonatal Murine β-Cells

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recommendations! Published in 2020 at "Diabetes"

DOI: 10.2337/db19-0906

Abstract: The N6-methyladenosine (m6A) RNA modification is essential during embryonic development of various organs. However, its role in embryonic and early postnatal islet development remains unknown. Mice in which RNA methyltransferase-like 3/14 (Mettl3/14) were deleted in… read more here.

Keywords: methylation controls; m6a mrna; mrna methylation; maturation ... See more keywords