New Twists in Detecting mRNA Modification Dynamics
Sign Up to like & getrecommendations! Published in 2020 at "Trends in Biotechnology"
DOI: 10.1016/j.tibtech.2020.06.002
Abstract: Modified nucleotides in mRNA are an essential addition to the standard genetic code of four nucleotides in animals, plants, and their viruses. The emerging field of epitranscriptomics examines nucleotide modifications in mRNA and their impact… read more here.
Keywords: mrna modification; new twists; twists detecting; detecting mrna ... See more keywords
The role of m6A mRNA modification in normal and malignant hematopoiesis.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of leukocyte biology"
DOI: 10.1093/jleuko/qiad061
Abstract: Hematopoiesis is a highly orchestrated biological process sustaining the supply of leukocytes involved in the maintenance of immunity, O2 and CO2 exchange, and wound healing throughout the life-time of an animal including human. During early… read more here.
Keywords: modification; malignant hematopoiesis; role m6a; mrna modification ... See more keywords
The Proteins of mRNA Modification: Writers, Readers, and Erasers.
Sign Up to like & getrecommendations! Published in 2023 at "Annual review of biochemistry"
DOI: 10.1146/annurev-biochem-052521-035330
Abstract: Over the past decade, mRNA modifications have emerged as important regulators of gene expression control in cells. Fueled in large part by the development of tools for detecting RNA modifications transcriptome wide, researchers have uncovered… read more here.
Keywords: modification; modification writers; proteins mrna; mrna modification ... See more keywords
NAT10 as a potential prognostic biomarker and therapeutic target for HNSCC
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Cell International"
DOI: 10.1186/s12935-021-02124-2
Abstract: Background Increasing evidence has demonstrated the critical roles of mRNA modification regulators on multiple types of cancers. However, it is still poorly known about the prognostic and therapeutic value of mRNA modification regulators in HNSCC.… read more here.
Keywords: mrna modification; analysis; hnscc; expression ... See more keywords
Uncovering N4-Acetylcytidine-Related mRNA Modification Pattern and Landscape of Stemness and Immunity in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.861000
Abstract: N4-acetylcytidine (ac4C) is an ancient and conserved RNA modification. Previously, ac4C mRNA modification has been reported promoting proliferation and metastasis of tumor cells. However, it remains unclear whether and how ac4C-related mRNA modification patterns influencing… read more here.
Keywords: modification; hepatocellular carcinoma; acetylcytidine; related mrna ... See more keywords
N6-methyladenosine-modified lncRNA and mRNA modification profiles in cerebral ischemia-reperfusion injury
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.973979
Abstract: Cerebral ischemia-reperfusion injury (CIRI) is common in ischemic stroke and seriously affects the prognosis of patients. At present, N6-methyladenosine (m6A) modification of lncRNAs and mRNAs has been reported in other diseases, such as cancer, but… read more here.
Keywords: reperfusion injury; modification; cerebral ischemia; mrna modification ... See more keywords