Profiling and Integrated Analysis of the ERCC6-regulated circRNA-miRNA-mRNA Network in Lens Epithelial Cells
Sign Up to like & getrecommendations! Published in 2021 at "Current Eye Research"
DOI: 10.1080/02713683.2021.1896742
Abstract: ABSTRACT Purpose: To explore the regulatory role of ERCC6 in the circRNA-miRNA-mRNA network using a cellular ERCC6 overexpression model (OE-ERCC6) in lens epithelial cells. Methods: The expression profiles of circRNAs, miRNAs and mRNAs were determined… read more here.
Keywords: mrna network; mirna mrna; circrna mirna;
An innovative systematic approach introduced the involved lncRNA-miR-mRNA network in cell cycle and proliferation after conventional treatments in breast cancer patients.
Sign Up to like & getrecommendations! Published in 2022 at "Cell cycle"
DOI: 10.1080/15384101.2022.2070104
Abstract: INTRODUCTION The present study aimed to explore the involved lncRNA-miRNA-mRNA network in the cell cycle and proliferation after conventional treatments in Luminal A breast cancer patients. METHODS The candidate miRNAs (miRs), lncRNAs, and mRNAs were… read more here.
Keywords: mrna network; cancer; cancer patients; breast cancer ... See more keywords
Integrated Microarray for Identifying the Hub mRNAs and Constructed MiRNA-mRNA Network in Coronary In-stent Restenosis.
Sign Up to like & getrecommendations! Published in 2022 at "Physiological genomics"
DOI: 10.1152/physiolgenomics.00089.2021
Abstract: As a major complication after percutaneous coronary intervention (PCI) in patients who suffer from coronary artery disease, in-stent restenosis (ISR) poses a significant challenge for clinical management. A miRNA-mRNA regulatory network of ISR can be… read more here.
Keywords: mrna network; network; mirna mrna; stent restenosis ... See more keywords
Identification of a transcription factor-microRNA network in esophageal adenocarcinoma through bioinformatics analysis and validation through qRT-PCR
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Management and Research"
DOI: 10.2147/cmar.s201274
Abstract: Purpose: The rapidly rising incidence of esophageal adenocarcinoma (EAC), which is usually diagnosed late with a poor prognosis, has become a growing problem. This study investigated the potential transcription factor (TF)-related molecular mechanisms of EAC… read more here.
Keywords: analysis; mrna network; qrt pcr; mirna mrna ... See more keywords
Integrated analysis of the lncRNA-miRNA-mRNA network based on competing endogenous RNA in atrial fibrillation
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2023.1099124
Abstract: Objective Long non-coding RNAs (lncRNAs) play pivotal roles in the transcriptional regulation of atrial fibrillation (AF) by acting as competing endogenous RNAs (ceRNAs). In the present study, the expression levels of lncRNAs of sinus rhythm… read more here.
Keywords: network; mirna mrna; network based; lncrna mirna ... See more keywords
Construction of a ceRNA-based lncRNA–mRNA network to identify functional lncRNAs in premature ovarian insufficiency
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.956805
Abstract: Premature ovarian insufficiency, characterized by ovarian infertility and low fertility, has become a significant problem in developed countries due to its propensity for late delivery. It has been described that the vital role of lncRNA… read more here.
Keywords: based lncrna; premature ovarian; ovarian insufficiency; lncrna mrna ... See more keywords
The Role of miR-4256/HOXC8 Signaling Axis in the Gastric Cancer Progression: Evidence From lncRNA-miRNA-mRNA Network Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.793678
Abstract: Gastric cancer is a deadly human malignancy and the molecular mechanisms underlying gastric cancer pathophysiology are very complicated. Thus, further investigations are warranted to decipher the underlying molecular mechanisms. With the development of high-throughput screening… read more here.
Keywords: hoxc8; mir 4256; gastric cancer; mrna network ... See more keywords
A systematic method introduced a common lncRNA-miRNA-mRNA network in the different stages of prostate cancer
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1142275
Abstract: Introduction The present study aimed to investigate the interaction of the common lncRNA-miRNA-mRNA network involved in signaling pathways in different stages of prostate cancer (PCa) by using bioinformatics and experimental methods. Methods Seventy subjects included… read more here.
Keywords: prostate cancer; common lncrna; mirna mrna; lncrna mirna ... See more keywords
Construction of miRNA-mRNA network reveals crucial miRNAs and genes in acute myocardial infarction
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biomedical Research"
DOI: 10.7555/jbr.35.20210088
Abstract: Acute myocardial infarction (AMI) is a severe cardiovascular disease. This study aimed to identify crucial microRNAs (miRNAs) and mRNAs in AMI by establishing a miRNA-mRNA network. The microarray datasets GSE31568, GSE148153, and GSE66360 were downloaded… read more here.
Keywords: mrna network; acute myocardial; mirna mrna; network ... See more keywords