Bridging mRNA and Polycation using RNA Oligonucleotide Derivatives Improves the Robustness of Polyplex Micelles for Efficient mRNA Delivery.
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DOI: 10.1002/adhm.202102016
Abstract: Polyplex for mRNA delivery requires strong yet reversible association between mRNA and polycation for extracellular robustness and selective intracellular disintegration. Herein, RNA oligonucleotide (OligoRNA) derivatives that bridge mRNA and polycation are developed to stabilize polyplex… read more here.
Keywords: polyplex micelles; mrna delivery; rna oligonucleotide; polycation ... See more keywords