IL-35 Detection in B Cells at the mRNA and Protein Level.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1237-8_8
Abstract: Emerging research suggests that IL-35-producing regulatory B cells accumulate in patients and mouse models of pancreatic cancer, one of the most lethal cancers, characterized by late diagnosis, high mortality, and morbidity. Identification of IL-35-producing B… read more here.
Keywords: cells mrna; detection; mrna protein; regulatory cells ... See more keywords
Effects of aging on protein expression in mice brain microvessels: ROS scavengers, mRNA/protein stability, glycolytic enzymes, mitochondrial complexes, and basement membrane components.
Sign Up to like & getrecommendations! Published in 2021 at "GeroScience"
DOI: 10.1007/s11357-021-00468-1
Abstract: Differentially expressed (DE) proteins in the cortical microvessels (MVs) of young, middle-aged, and old male and female mice were evaluated using discovery-based proteomics analysis (> 4,200 quantified proteins/group). Most DE proteins (> 90%) showed no significant differences… read more here.
Keywords: old mice; mrna protein; basement membrane; protein stability ... See more keywords
The Alleviative Efficacy of Vitamins A, C, and E Against Zinc Oxide Nanoparticles-Induced Hepatic Damage by Reducing Apoptosis in Rats.
Sign Up to like & getrecommendations! Published in 2022 at "Biological trace element research"
DOI: 10.1007/s12011-022-03218-2
Abstract: Nanoparticles are vastly exploited in today's technology. However, it is realized that exposure to high concentrations of nanoparticles (NPs) may have adverse effects on human health. According to previous reports, zinc oxide (ZnO) NPs cause… read more here.
Keywords: damage; apoptosis; zinc oxide; zno ... See more keywords
Angiotensin type 2 receptors: Role in aging and neuroinflammation in the substantia nigra
Sign Up to like & getrecommendations! Published in 2020 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2019.12.011
Abstract: Overactivity of the angiotensin-type-1 receptor (AT1)/NADPH-oxidase axis enhances aging processes, neuroinflammation and neurodegeneration. The role of AT2 receptors in the above-mentioned AT1-related effects in the aged brain, particularly substantia nigra, was investigated in this study.… read more here.
Keywords: mrna protein; expression; angiotensin; type ... See more keywords
Discordant mRNA and protein expression of CXCR4 under in vitro CoCl2-induced hypoxic conditions.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.01.102
Abstract: Cobalt chloride (CoCl2) has long been accepted as a suitable in vitro hypoxia-mimetic agent. The gene CXCR4, which encodes a chemokine receptor, plays a key role in hypoxic retinal disease. Here, we investigated the mRNA and… read more here.
Keywords: mrna protein; hypoxic conditions; cocl2 induced; cocl2 ... See more keywords
Distinct characteristics of nasal polyps with and without eosinophilia.
Sign Up to like & getrecommendations! Published in 2017 at "Brazilian journal of otorhinolaryngology"
DOI: 10.1016/j.bjorl.2016.01.012
Abstract: INTRODUCTION Eosinophilic and noneosinophilic Nasal polyps (NPs) are different subtypes of NPs and require different treatment methods. OBJECTIVE To compare the histologic characteristics, mRNA and protein expression between Nasal Polyps with and without eosinophilia. METHODS… read more here.
Keywords: protein expression; mrna protein; noneosinophilic nps; nasal polyps ... See more keywords
Multivariate Control of Transcript to Protein Variability in Single Mammalian Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Cell systems"
DOI: 10.1016/j.cels.2018.09.001
Abstract: A long-standing question in quantitative biology is the relationship between mRNA and protein levels of the same gene. Here, we measured mRNA and protein abundance, the phenotypic state, and the population context in thousands of… read more here.
Keywords: cell; mrna protein; protein abundance; phenotypic state ... See more keywords
Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses
Sign Up to like & getrecommendations! Published in 2021 at "Immunity"
DOI: 10.1016/j.immuni.2021.11.001
Abstract: Adjuvants are critical for improving the quality and magnitude of adaptive immune responses to vaccination. Lipid nanoparticle (LNP)-encapsulated nucleoside-modified mRNA vaccines have shown great efficacy against SARS-CoV-2, but the mechanism of action of this vaccine… read more here.
Keywords: mrna protein; protein subunit; helper cell; follicular helper ... See more keywords
Antagonistic effects of selenium against necroptosis injury via adiponectin-necrotic pathway induced by cadmium in heart of chicken
Sign Up to like & getrecommendations! Published in 2017 at "RSC Advances"
DOI: 10.1039/c7ra07952d
Abstract: Cadmium (Cd) is one of the most toxic heavy metals having a destructive impact on various organ systems. For example, it induces oxidative stress in heart of chicken. Selenium (Se), in the form of selenoproteins,… read more here.
Keywords: mrna protein; heart; heart chicken; pathway ... See more keywords
Alterations of the Extracellular Matrix in Colorectal Carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Genetic testing and molecular biomarkers"
DOI: 10.1089/gtmb.2021.0209
Abstract: Background: The process of proliferation and invasion of tumor cells depends on changes in the extracellular matrix (ECM) through the activation of enzymes and alterations in the profile of ECM components. Our aims are to… read more here.
Keywords: extracellular matrix; mrna protein; ecm components; expression ... See more keywords
SPP1 expression in the mouse uterus and placenta: implications for implantation
Sign Up to like & getrecommendations! Published in 2021 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioab125
Abstract: Abstract Secreted phosphoprotein 1 (SPP1, also known as osteopontin) binds integrins to mediate cell–cell and cell–extracellular matrix communication to promote cell adhesion, migration, and differentiation. Considerable evidence links SPP1 to pregnancy in several species. Current… read more here.
Keywords: mrna protein; spp1 expression; implantation; spp1 mrna ... See more keywords