Quantification of mRNA in Single Cells Based on Dimerization-Induced Photoluminescence Nonblinking of Quantum Dots.
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DOI: 10.1021/acs.analchem.2c02209
Abstract: Photoluminescence (PL) intermittency (or "blinking") is a unique characteristic of single quantum dot (QD) emission. Here, we report a novel single-molecule detection strategy for the intracellular mRNA of interest using the mRNA-induced nonblinking QD dimers… read more here.
Keywords: photoluminescence; dna; mrna single; target dna ... See more keywords