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   Articles with "mrna structure" as a keyword



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The role of mRNA structure in bacterial translational regulation

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recommendations! Published in 2017 at "Wiley Interdisciplinary Reviews: RNA"

DOI: 10.1002/wrna.1370

Abstract: The characteristics of bacterial messenger RNAs (mRNAs) that influence translation efficiency provide many convenient handles for regulation of gene expression, especially when coupled with the processes of transcription termination and mRNA degradation. An mRNA's structure,… read more here.

Keywords: translational regulation; mrna structure; bacterial translational; structure ... See more keywords
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Adaptation of mRNA structure to control protein folding

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recommendations! Published in 2017 at "RNA Biology"

DOI: 10.1080/15476286.2017.1349047

Abstract: ABSTRACT Comparison of mRNA and protein structures shows that highly structured mRNAs typically encode compact protein domains suggesting that mRNA structure controls protein folding. This function is apparently performed by distinct structural elements in the… read more here.

Keywords: protein; structure control; mrna structure; protein folding ... See more keywords
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The importance of mRNA structure in determining the pathogenicity of synonymous and non‐synonymous mutations in haemophilia

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recommendations! Published in 2017 at "Haemophilia"

DOI: 10.1111/hae.13107

Abstract: Mutational analysis is commonly used to support the diagnosis and management of haemophilia. This has allowed for the generation of large mutation databases which provide unparalleled insight into genotype–phenotype relationships. Haemophilia is associated with inversions,… read more here.

Keywords: synonymous non; synonymous mutations; mrna structure; structure determining ... See more keywords
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Allele-specific SHAPE-MaP assessment of the effects of somatic variation and protein binding on mRNA structure.

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recommendations! Published in 2018 at "RNA"

DOI: 10.1261/rna.064469.117

Abstract: The impact of inherited and somatic mutations on messenger RNA (mRNA) structure remains poorly understood. Recent technological advances that leverage next-generation sequencing to obtain experimental structure data, such as SHAPE-MaP, can reveal structural effects of… read more here.

Keywords: mrna structure; tpt1 lcp1; structure; shape map ... See more keywords