Quantification of mRNA Turnover in Living Cells: A Pipeline for TREAT Data Analysis.
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DOI: 10.1007/978-1-4939-9674-2_6
Abstract: mRNA turnover plays an important role in the regulation of post-transcriptional gene expression. While many protein factors involved in mRNA degradation have been identified, we still lack a basic understanding of the principles that regulate… read more here.
Keywords: mrna turnover; treat; pipeline; turnover ... See more keywords
Antagonistic actions of two human Pan3 isoforms on global mRNA turnover.
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DOI: 10.1261/rna.061556.117
Abstract: Deadenylation is a fundamental process that regulates eukaryotic gene expression. Mammalian deadenylation exhibits biphasic kinetics, with the Pan2-Pan3 and Ccr4-Caf1 deadenylase complexes mediating the first and second phase, respectively; however, the significance of the biphasic… read more here.
Keywords: turnover; mrna turnover; human pan3; pan3 isoforms ... See more keywords