Identification of tumor antigens and immune subtypes of glioma for mRNA vaccine development
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4633
Abstract: Recent evidence suggested that the mRNA vaccine has been effective for many tumors, but its progress in gliomas was slow. In this study, we screened potential tumor antigens and suitable populations for mRNA vaccine to… read more here.
Keywords: mrna vaccine; immune subtypes; tumor antigens; vaccine ... See more keywords
Six‐months immunogenicity of BNT162b2 mRNA vaccine in heart transplanted and ventricle assist device‐supported patients
Sign Up to like & getrecommendations! Published in 2022 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13798
Abstract: To assess the 6 months immunogenicity to severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) mRNA vaccine in a population of heart transplanted (HTx) recipients and left ventricular assist device (LVAD)‐supported patients. read more here.
Keywords: supported patients; heart transplanted; months immunogenicity; heart ... See more keywords
Effectiveness of a third dose of BNT162b2 anti-SARS-CoV-2 mRNA vaccine over a 6-month follow-up period in allogenic hematopoietic stem cells recipients.
Sign Up to like & getrecommendations! Published in 2022 at "Hematological oncology"
DOI: 10.1002/hon.3006
Abstract: This study reports the effectiveness of three injections of BNT162b2 anti-SARS-CoV-2 mRNA vaccine in 141 Allo-HSCT recipients with a median follow-up of 6 months post-third shot. We demonstrate a long-term high protection of Allo-HSCT recipients… read more here.
Keywords: cov mrna; anti sars; bnt162b2 anti; mrna vaccine ... See more keywords
Immunogenicity and safety of the BNT162b2 COVID‐19 mRNA vaccine in PLWH: A monocentric study in Bari, Italy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27629
Abstract: In March, people living with HIV infection (PLWH) were included in the risk category of fragile people for severe COVID‐19 receiving priority access to vaccination with BNT162b2 vaccine. The aim of the study was to… read more here.
Keywords: time; bnt162b2; mrna vaccine; immunogenicity safety ... See more keywords
Durability of humoral and cell‐mediated immune response after SARS‐CoV‐2 mRNA vaccine administration
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28360
Abstract: Vaccination against the SARS‐Cov‐2 virus is an effective way to protect against the disease and the severe course of COVID‐19. Forty‐nine fully vaccinated with mRNA vaccines (BNT162b2 or mRNA‐1273) SARS‐CoV‐2 infection‐naïve volunteers aged 33–89 were… read more here.
Keywords: response; response sars; immune response; mrna vaccine ... See more keywords
Systemic IL-15, IFN-γ, and IP-10/CXCL10 signature associated with effective immune response to SARS-CoV-2 in BNT162b2 mRNA vaccine recipients
Sign Up to like & getrecommendations! Published in 2021 at "Cell Reports"
DOI: 10.1016/j.celrep.2021.109504
Abstract: Early responses to vaccination are important in shaping both humoral and cellular protective immunity. Dissecting innate vaccine signatures may predict immunogenicity to help optimizing efficacy of mRNA and other vaccine strategies. We characterized the cytokine… read more here.
Keywords: response; vaccine; mrna vaccine; ifn cxcl10 ... See more keywords
Serological response to a single dose of a SARS-CoV-2 mRNA vaccine
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Virological Methods"
DOI: 10.1016/j.jviromet.2021.114223
Abstract: The delays in the production and delivery of COVID-19 vaccines and the growing number of fatal infections across the globe raised the question whether it would be more advantageous to vaccinate a larger group of… read more here.
Keywords: response; mrna vaccine; serological response; response single ... See more keywords
Addressing the Cold Reality of mRNA Vaccine Stability
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DOI: 10.1016/j.xphs.2020.12.006
Abstract: As mRNA vaccines became the frontrunners in late-stage clinical trials to fight the COVID-19 pandemic, challenges surrounding their formulation and stability became readily apparent. In this commentary, we first describe company proposals, based on available… read more here.
Keywords: storage; mrna vaccine; addressing cold; stability ... See more keywords
A paediatric case of myopericarditis post-COVID-19 mRNA vaccine
Sign Up to like & getrecommendations! Published in 2022 at "Cardiology in the Young"
DOI: 10.1017/s1047951122000312
Abstract: Myopericarditis is a condition, which primarily involves the pericardium, with minimal myocardial involvement. In myopericarditis, chest pain, elevated cardiac enzymes, and electrocardiographic changes occur. Although COVID-19 mRNA vaccines significantly contribute to preventing the COVID-19 disease,… read more here.
Keywords: paediatric case; myopericarditis; covid; covid mrna ... See more keywords
Investigating Generation of Antibodies against the Lipid Nanoparticle Vector Following COVID-19 Vaccination with an mRNA Vaccine.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c01036
Abstract: Despite the success of mRNA-based vaccines against infectious diseases (including COVID-19), safety concerns have been raised relating to the lipid nanoparticles (LNPs) used to deliver the mRNA cargo. Antibodies against the polyethylene glycol (PEG) coating… read more here.
Keywords: vaccination; plasma concentration; vaccine; mrna vaccine ... See more keywords
SARS-CoV-2 mRNA Vaccine Design Enabled by Prototype Pathogen Preparedness
Sign Up to like & getrecommendations! Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-2622-0
Abstract: A vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is needed to control the coronavirus disease 2019 (COVID-19) global pandemic. Structural studies have led to the development of mutations that stabilize Betacoronavirus spike proteins… read more here.
Keywords: vaccine; mrna vaccine; mrna 1273; sars cov ... See more keywords