Bacterial Toxin‐Triggered Release of Antibiotics from Capsosomes Protects a Fly Model from Lethal Methicillin‐Resistant Staphylococcus aureus (MRSA) Infection
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200036
Abstract: Antibiotic resistance is a severe global health threat and hence demands rapid action to develop novel therapies, including microscale drug delivery systems. Herein, a hierarchical microparticle system is developed to achieve bacteria‐activated single‐ and dual‐antibiotic… read more here.
Keywords: methicillin resistant; staphylococcus aureus; aureus mrsa; mrsa infection ... See more keywords
Guanidinium‐Decorated Nanostructure for Precision Sonodynamic‐Catalytic Therapy of MRSA‐Infected Osteomyelitis
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202206646
Abstract: Osteomyelitis caused by methicillin‐resistant Staphylococcus aureus (MRSA) biofilm infection is difficult to eradicate and can even be life‐threatening. Given that the infection is persistent and deep‐seated in the bone tissue, controlled and efficient treatment of… read more here.
Keywords: catalytic therapy; osteomyelitis; therapy; guanidinium ... See more keywords
Iron‐Single‐Atom Nanozyme with NIR Enhanced Catalytic Activities for Facilitating MRSA‐Infected Wound Therapy
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202308684
Abstract: Patients with methicillin‐resistant Staphylococcus aureus (MRSA) infections may have higher death rates than those with non‐drug‐resistant infections. Nanozymes offer a promising approach to eliminating bacteria by producing reactive oxygen species. However, most of the conventional… read more here.
Keywords: atom; mrsa; single atom; atom nanozyme ... See more keywords
Anthraquinone-based Ligand as MNase Inhibitor: Insights from Inhibition Studies and Generation of a Payload Nanocarrier for Potential Anti-MRSA Therapy.
Sign Up to like & getrecommendations! Published in 2023 at "ChemMedChem"
DOI: 10.1002/cmdc.202200711
Abstract: The present study highlights the prospect of an anthraquinone-based ligand (C1) as an inhibitor of micrococcal nuclease (MNase) enzyme secreted by Staphylococcus aureus. MNase inhibition rendered by 5.0 µM C1 was ~96% and the ligand… read more here.
Keywords: inhibition; mnase; based ligand; anthraquinone based ... See more keywords
Discovery of novel halogenated 8‐hydroxyquinoline‐based anti‐MRSA agents: In vitro and QSAR studies
Sign Up to like & getrecommendations! Published in 2019 at "Drug Development Research"
DOI: 10.1002/ddr.21611
Abstract: Methicillin‐resistant Staphylococcus aureus (MRSA) infection has been considered to be one of global health problems due to limited classes of effective antimicrobial drugs. Herein, 8‐hydroxyquinoline (8HQ) and its derivatives (1‐7) were investigated for their anti‐MRSA… read more here.
Keywords: anti mrsa; novel halogenated; hydroxyquinoline; discovery novel ... See more keywords
Investigating the Prevalence of Enterotoxin and Antibiotic Resistance in Methicillin‐Resistant Staphylococcus aureus (MRSA) Isolated From Meat and Edible Viscera of Broiler Chickens
Sign Up to like & getrecommendations! Published in 2025 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.70413
Abstract: ABSTRACT Background The responsible for staph infection is methicillin‐resistant Staphylococcus aureus (MRSA) which has a long and difficult treatment process due to resistance to this type of antibiotic. This study is designed to investigate the… read more here.
Keywords: resistance; mrsa; meat edible; viscera broiler ... See more keywords
Tonsillektomie zur MRSA‑Sanierung – eine Kasuistik
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DOI: 10.1007/s00106-018-0581-7
Abstract: ZusammenfassungEs wird über einen Klinikarzt berichtet, bei dem nach 3 erfolglosen Eradikationsversuchen wegen einer nasopharyngealen MRSA(Methicillin-resistenter Staphylokokkus ausreus)‑Besiedlung mit langfristigem Erfolg eine Tonsillektomie durchgeführt wurde.AbstractHerein is reported the case of a clinician in whom, after three unsuccessful… read more here.
Keywords: sanierung eine; eine kasuistik; mrsa sanierung; mrsa ... See more keywords
Detection of MRSA of Lineages CC130-mecC and CC398-mecA and Staphylococcus delphini-lnu(A) in Magpies and Cinereous Vultures in Spain
Sign Up to like & getrecommendations! Published in 2019 at "Microbial Ecology"
DOI: 10.1007/s00248-019-01328-4
Abstract: The aim of this study was to determine the carriage rate of coagulase-positive staphylococci (CoPS) in wild birds and to characterize recovered isolates. Tracheal samples from 324 wild birds, obtained in different Spanish regions during… read more here.
Keywords: cc398; delphini; resistance; mrsa ... See more keywords
Catechin isolated from cashew nut shell exhibits antibacterial activity against clinical isolates of MRSA through ROS-mediated oxidative stress.
Sign Up to like & getrecommendations! Published in 2020 at "Applied microbiology and biotechnology"
DOI: 10.1007/s00253-020-10853-z
Abstract: Staphylococcus aureus causes severe infections and among all methicillin-resistant S. aureus (MRSA) remains a great challenge in spite of decade research of antibacterial compounds. Even though some synthetic antibiotics have been developed, they are not… read more here.
Keywords: catechin; cashew nut; nut shell; mrsa ... See more keywords
A cross-sectional study of methicillin-resistant Staphylococcus aureus at the equine-human interface
Sign Up to like & getrecommendations! Published in 2019 at "Tropical Animal Health and Production"
DOI: 10.1007/s11250-019-01888-0
Abstract: The present study aimed at investigating the percent prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in equines and associated personnel. A total of 150 swabs of equines and 50 nasal swab samples of associated personnel were… read more here.
Keywords: staphylococcus aureus; aureus; resistant staphylococcus; methicillin resistant ... See more keywords
Heartfelt Impact: A Descriptive Analysis of Ceftaroline-Containing Regimens in Endocarditis due to Methicillin-Resistant Staphylococcus aureus
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DOI: 10.1007/s40121-024-01068-0
Abstract: Infective endocarditis (IE) due to methicillin-resistant Staphylococcus aureus (MRSA) is characterized by frequent treatment failure to first-line agents and high mortality, necessitating use of alternative management strategies. Ceftaroline fosamil (CPT) is a cephalosporin antibiotic with… read more here.
Keywords: mrsa; endocarditis due; culture; resistant staphylococcus ... See more keywords