Bacterial Toxin‐Triggered Release of Antibiotics from Capsosomes Protects a Fly Model from Lethal Methicillin‐Resistant Staphylococcus aureus (MRSA) Infection
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200036
Abstract: Antibiotic resistance is a severe global health threat and hence demands rapid action to develop novel therapies, including microscale drug delivery systems. Herein, a hierarchical microparticle system is developed to achieve bacteria‐activated single‐ and dual‐antibiotic… read more here.
Keywords: methicillin resistant; staphylococcus aureus; aureus mrsa; mrsa infection ... See more keywords
Guanidinium‐Decorated Nanostructure for Precision Sonodynamic‐Catalytic Therapy of MRSA‐Infected Osteomyelitis
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202206646
Abstract: Osteomyelitis caused by methicillin‐resistant Staphylococcus aureus (MRSA) biofilm infection is difficult to eradicate and can even be life‐threatening. Given that the infection is persistent and deep‐seated in the bone tissue, controlled and efficient treatment of… read more here.
Keywords: catalytic therapy; osteomyelitis; therapy; guanidinium ... See more keywords
Anthraquinone-based Ligand as MNase Inhibitor: Insights from Inhibition Studies and Generation of a Payload Nanocarrier for Potential Anti-MRSA Therapy.
Sign Up to like & getrecommendations! Published in 2023 at "ChemMedChem"
DOI: 10.1002/cmdc.202200711
Abstract: The present study highlights the prospect of an anthraquinone-based ligand (C1) as an inhibitor of micrococcal nuclease (MNase) enzyme secreted by Staphylococcus aureus. MNase inhibition rendered by 5.0 µM C1 was ~96% and the ligand… read more here.
Keywords: inhibition; mnase; based ligand; anthraquinone based ... See more keywords
Discovery of novel halogenated 8‐hydroxyquinoline‐based anti‐MRSA agents: In vitro and QSAR studies
Sign Up to like & getrecommendations! Published in 2019 at "Drug Development Research"
DOI: 10.1002/ddr.21611
Abstract: Methicillin‐resistant Staphylococcus aureus (MRSA) infection has been considered to be one of global health problems due to limited classes of effective antimicrobial drugs. Herein, 8‐hydroxyquinoline (8HQ) and its derivatives (1‐7) were investigated for their anti‐MRSA… read more here.
Keywords: anti mrsa; novel halogenated; hydroxyquinoline; discovery novel ... See more keywords
Tonsillektomie zur MRSA‑Sanierung – eine Kasuistik
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DOI: 10.1007/s00106-018-0581-7
Abstract: ZusammenfassungEs wird über einen Klinikarzt berichtet, bei dem nach 3 erfolglosen Eradikationsversuchen wegen einer nasopharyngealen MRSA(Methicillin-resistenter Staphylokokkus ausreus)‑Besiedlung mit langfristigem Erfolg eine Tonsillektomie durchgeführt wurde.AbstractHerein is reported the case of a clinician in whom, after three unsuccessful… read more here.
Keywords: sanierung eine; eine kasuistik; mrsa sanierung; mrsa ... See more keywords
Detection of MRSA of Lineages CC130-mecC and CC398-mecA and Staphylococcus delphini-lnu(A) in Magpies and Cinereous Vultures in Spain
Sign Up to like & getrecommendations! Published in 2019 at "Microbial Ecology"
DOI: 10.1007/s00248-019-01328-4
Abstract: The aim of this study was to determine the carriage rate of coagulase-positive staphylococci (CoPS) in wild birds and to characterize recovered isolates. Tracheal samples from 324 wild birds, obtained in different Spanish regions during… read more here.
Keywords: cc398; delphini; resistance; mrsa ... See more keywords
Catechin isolated from cashew nut shell exhibits antibacterial activity against clinical isolates of MRSA through ROS-mediated oxidative stress.
Sign Up to like & getrecommendations! Published in 2020 at "Applied microbiology and biotechnology"
DOI: 10.1007/s00253-020-10853-z
Abstract: Staphylococcus aureus causes severe infections and among all methicillin-resistant S. aureus (MRSA) remains a great challenge in spite of decade research of antibacterial compounds. Even though some synthetic antibiotics have been developed, they are not… read more here.
Keywords: catechin; cashew nut; nut shell; mrsa ... See more keywords
A cross-sectional study of methicillin-resistant Staphylococcus aureus at the equine-human interface
Sign Up to like & getrecommendations! Published in 2019 at "Tropical Animal Health and Production"
DOI: 10.1007/s11250-019-01888-0
Abstract: The present study aimed at investigating the percent prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in equines and associated personnel. A total of 150 swabs of equines and 50 nasal swab samples of associated personnel were… read more here.
Keywords: staphylococcus aureus; aureus; resistant staphylococcus; methicillin resistant ... See more keywords
Livestock-Associated Meticillin-Resistant Staphylococcus aureus—Current Situation and Impact From a One Health Perspective
Sign Up to like & getrecommendations! Published in 2021 at "Current Clinical Microbiology Reports"
DOI: 10.1007/s40588-021-00170-y
Abstract: In this article, we aim to provide an overview of the occurrence and characteristics of livestock-associated (LA-) meticillin-resistant Staphylococcus aureus (MRSA). We further question the role of LA-MRSA as a potential foodborne pathogen. We investigate… read more here.
Keywords: meticillin resistant; livestock associated; resistant staphylococcus; associated meticillin ... See more keywords
[Rate of methicillin-resistant Staphylococcus aureus in pediatric emergency departments in Spain].
Sign Up to like & getrecommendations! Published in 2021 at "Anales de pediatria"
DOI: 10.1016/j.anpedi.2021.06.013
Abstract: INTRODUCTION Staphylococcusaureus (S. aureus) is a common germ present in bacterial infections in children. Lately, the rate of methicillin-resistant S. aureus (MRSA) is increasing. OBJECTIVES The main aim of this study is to know the… read more here.
Keywords: pediatric emergency; emergency departments; mrsa; rate ... See more keywords
Influence of biofilm-forming lactic acid bacteria against methicillin-resistant Staphylococcus aureus (MRSA S547)
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DOI: 10.1016/j.apjtb.2017.10.013
Abstract: Abstract Objective To investigate the antibacterial effect of selected lactic acid bacteria (LAB) biofilms on the planktonic and biofilm population of methicillin-resistant Staphylococcus aureus (MRSA) (S547). Methods In this study, biofilm-forming LAB were isolated from… read more here.
Keywords: plantarum; mrsa s547; biofilm; mrsa ... See more keywords