Synthesis and antibacterial evaluation of 13-substituted cycloberberine derivatives as a novel class of anti-MRSA agents.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.08.050
Abstract: A series of new 13-substituted cycloberberine (CBBR) derivatives were prepared and evaluated for their antibacterial activities against Gram-positive bacteria taking CBBR as the lead. Structure-activity relationship revealed that the introduction of a suitable electron-donating group… read more here.
Keywords: substituted cycloberberine; anti mrsa; derivatives novel; mrsa agents ... See more keywords
In vitro anti-biofilm effect of anti-methicillin-resistant Staphylococcus aureus (MRSA) agents against the USA300 clone.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2020.11.026
Abstract: OBJECTIVES Infection with a typical community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), the USA300 clone, has become a worldwide epidemic. The formation of biofilms at the site of infection is one of the reasons for the development… read more here.
Keywords: anti mrsa; mrsa agents; biofilm; usa300 clone ... See more keywords
Discovery of New Anti-MRSA Agents Based on Phenoxyethanol and Its Mechanism.
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DOI: 10.1021/acsinfecdis.2c00365
Abstract: Methicillin-resistant Staphylococcus aureus (MRSA) poses a severe threat to public health and safety. The discovery and development of novel anti-MRSA drugs with a new mode of action are a challenge. In this study, a class… read more here.
Keywords: mrsa agents; compound; based phenoxyethanol; anti mrsa ... See more keywords
Prospective audit and feedback implementation by a multidisciplinary antimicrobial stewardship team shortens the time to de-escalation of anti-MRSA agents
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0271812
Abstract: Prospective audit and feedback (PAF) is considered an effective procedure for appropriate antibiotic use. However, its effect on the time to de-escalation is unclear. We aimed to evaluate the effect of daily PAF implementation, focusing… read more here.
Keywords: time; paf; time escalation; mrsa agents ... See more keywords