The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk
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DOI: 10.1126/scitranslmed.aau2291
Abstract: Common variants in the microglia-specific MS4A gene cluster modify risk for late-onset Alzheimer’s disease and modulate extracellular soluble TREM2. TREM2 takes center stage Genetic variants in triggering receptor expressed on myeloid cells 2 (TREM2) are… read more here.
Keywords: risk; alzheimer disease; ms4a gene; disease ... See more keywords