Is multiple system atrophy an infectious disease?
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Neurology"
DOI: 10.1002/ana.25132
Abstract: Multiple system atrophy (MSA) is a fatal neurodegenerative disorder that causes autonomic failure, parkinsonism, and cerebellar ataxia in any combination. Pathological hallmarks of this condition are a-synucleinrich glial cytoplasmatic inclusions (GCIs). Misfolded a-synuclein aggregates can… read more here.
Keywords: system; synuclein; prion; disease ... See more keywords
Nocturnal Pulse Event Frequency Is Reduced in Multiple System Atrophy
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DOI: 10.1002/ana.26533
Abstract: Risk of sudden death in multiple system atrophy (MSA) is greatest during sleep with unknown mechanisms. We compared nocturnal pulse event frequency in 46 MSA patients and age‐/sex‐matched controls undergoing overnight pulse oximetry. Nocturnal oxyhemoglobin… read more here.
Keywords: nocturnal pulse; pulse event; event frequency; msa ... See more keywords
Author response to: Comment on: Systematic review of the introduction and evaluation of magnetic augmentation of the lower oesophageal sphincter for gastro‐oesophageal reflux disease
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Surgery"
DOI: 10.1002/bjs.11565
Abstract: Editor We thank Bonavina et al. for their correspondence. We are delighted they agree that a well-designed and conducted RCT to compare the effectiveness of magnetic sphincter augmentation (MSA) and anti-reflux surgery is required to… read more here.
Keywords: reflux; sphincter; augmentation; review ... See more keywords
Comment on: Systematic review of the introduction and evaluation of magnetic augmentation of the lower oesophageal sphincter for gastro‐oesophageal reflux disease
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Surgery"
DOI: 10.1002/bjs.11567
Abstract: Editor Kirkham et al.1 concluded in their review of the current evidence for magnetic sphincter augmentation (MSA) that it is ‘being used despite a lack of robust evidence for its effectiveness’. We disagree. Their study… read more here.
Keywords: introduction; sphincter; evidence; augmentation ... See more keywords
Alterations of voxel‐wise spontaneous activity and corresponding brain functional networks in multiple system atrophy patients with mild cognitive impairment
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DOI: 10.1002/hbm.26058
Abstract: Emerging evidence has indicated that cognitive impairment is an underrecognized feature of multiple system atrophy (MSA). Mild cognitive impairment (MCI) is related to a high risk of dementia. However, the mechanism underlying MCI in MSA… read more here.
Keywords: msa; cognitive impairment; activity; atrophy ... See more keywords
Functional connectome automatically differentiates multiple system atrophy (parkinsonian type) from idiopathic Parkinson's disease at early stages
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DOI: 10.1002/hbm.26201
Abstract: Differentiating the parkinsonian variant of multiple system atrophy (MSA‐P) from idiopathic Parkinson's disease (IPD) is challenging, especially in the early stages. This study aimed to investigate differences and similarities in the brain functional connectomes of… read more here.
Keywords: functional connectome; msa; multiple system; system atrophy ... See more keywords
SPG7: The Great Imitator of MSA‐C Within the ILOCAs
Sign Up to like & getrecommendations! Published in 2019 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.12711
Abstract: Idiopathic late-onset cerebellar ataxia (ILOCA) was introduced by A. Harding in 1981. The term described patients, starting around the age of 50, with slowly progressive cerebellar ataxia (CA) of unknown cause, sometimes associated with other… read more here.
Keywords: msa within; great imitator; ataxia; imitator msa ... See more keywords
Functional expression of monomeric streptavidin and fusion proteins in Escherichia coli: applications in flow cytometry and ELISA
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DOI: 10.1007/s00253-018-9377-7
Abstract: Monomeric streptavidin (mSA) offers a combination of structural and binding properties that are useful in many applications, including a small size and monovalent biotin binding. Because mSA contains a structurally important disulfide bond, the molecule does… read more here.
Keywords: escherichia coli; msa; monomeric streptavidin; flow cytometry ... See more keywords
Anatomical study of medial sural artery and its perforators in Nepalese: an aid to reconstructive surgery
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DOI: 10.1007/s00276-017-1956-2
Abstract: ObjectiveThe present study was undertaken to know the anatomical basis of medial sural artery (MSA) and its perforators in Nepalese.MethodsThe popliteal arteries of 16 preserved cadaveric lower limbs were injected with a mixture of red… read more here.
Keywords: artery; sural artery; study; msa ... See more keywords
Abnormalities of white and grey matter in early multiple system atrophy: comparison of parkinsonian and cerebellar variants
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DOI: 10.1007/s00330-018-5594-9
Abstract: ObjectiveMultiple system atrophy (MSA) is a neurodegenerative disorder with progressive motor and autonomic dysfunction. There is a paucity of information on the early neurostructural changes in MSA, especially its subtypes, MSA-P (patients with predominant parkinsonism)… read more here.
Keywords: structural changes; grey matter; matter early; system atrophy ... See more keywords
Distinctive speech signature in cerebellar and parkinsonian subtypes of multiple system atrophy
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DOI: 10.1007/s00415-019-09271-7
Abstract: Although motor speech disorders represent an early and prominent clinical feature of multiple system atrophy (MSA), the potential usefulness of speech assessment as a diagnostic tool has not yet been explored. This cross-sectional study aimed… read more here.
Keywords: speech; system atrophy; distinctive speech; msa ... See more keywords